A multiple respiratory antigen detection card and kit

Abstract

The invention relates to a multi-respiratory tract antigen detection card, which includes influenza A virus antigen test strips, influenza B virus antigen test strips, respiratory adenovirus antigen test strips, respiratory syncytial virus antigen test strips and Mycoplasma pneumoniae antigen test strips, Influenza A virus antigen test strips, Influenza B virus antigen test strips, Respiratory adenovirus antigen test strips, Respiratory syncytial virus antigen test strips and Mycoplasma pneumoniae antigen test strips all include Colloidal gold conjugate pads, colloidal gold conjugate pads include streptavidin conjugate pads and double-nanoparticle double-labeled antibody conjugate pads; the test strips in this test card can fully react biological raw materials and improve the sensitivity of antigen detection , effectively reducing missed detection, and adding blocking agents to the sample pad to improve specificity, and can simultaneously detect influenza A virus, influenza B virus, respiratory adenovirus, respiratory syncytial virus, and Mycoplasma pneumoniae antigens.

Description

technical field [0001] The invention relates to the field of human respiratory virus detection, in particular to an antigen detection card and kit for influenza A virus, influenza B virus, respiratory adenovirus, respiratory syncytial virus and mycoplasma pneumoniae. Background technique [0002] There are three types of influenza virus, A, B, and C. Type A is the most likely to cause epidemics, followed by Type B, and Type C rarely causes epidemics. According to the antigenicity of outer membrane phytohemagglutinin (HA) and neuraminidase (NA) proteins, influenza A virus can be divided into 15 H subtypes (H1-H15) and 9 N subtypes (N1-H15). ~N9). Because the nucleic acid sequences encoding HA and (or) NA are prone to mutations, resulting in changes in the antigenic epitopes of HA and (or) NA, this antigenic change makes the original specific immunity of the population invalid, so influenza A Viruses often cause large-scale or even worldwide influenza epidemics. Most suscep...

AI Technical Summary

Problems solved by technology

Isolation and culture have diagnostic significance, but the rate of missed diagnosis is high. Therefore, serotype detection is mostly used for diagnosis in the later stage. Antigen detection, with its advantages of high sensitivity and specificity, gradually replaces serological detection and plays an important role in the prevention of pathogen infection. , diagnosis, treatment, and prognosis