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Pelteobagrus fulvidraco mixed bacterium inactivated vaccine

An inactivated vaccine and yellow catfish technology, applied in the field of bioengineering, can solve problems such as unreported research, achieve high application value, reduce damage, and reduce the number of immunizations

Pending Publication Date: 2021-03-02
GUANGXI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

According to the preliminary investigation of our laboratory, it is found that Guangxi yellow catfish is often caused by the mixed infection of various pathogenic bacteria, but there is no report on the research on the mixed bacterial inactivated vaccine of yellow catfish

Method used

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  • Pelteobagrus fulvidraco mixed bacterium inactivated vaccine
  • Pelteobagrus fulvidraco mixed bacterium inactivated vaccine
  • Pelteobagrus fulvidraco mixed bacterium inactivated vaccine

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Embodiment Construction

[0022] The scheme of the present invention will be further described in detail below in conjunction with the examples. The following description is only for explaining the present invention, and does not limit its content. The experimental methods used in the following examples are conventional methods unless otherwise specified, and the materials and reagents used in the following examples can be obtained from commercial sources unless otherwise specified.

[0023] 1 Materials and methods

[0024] 1.1 Experimental materials

[0025] Healthy yellow catfish was purchased from a farm in Nanning, Guangxi, with a weight of about (14.1±1.2) g. They were sterilized with 2.5% salt water before stocking. Individuals with lively movements, no injuries in appearance, and the same specifications were selected and placed in the fishery of Guangxi University. In the experimental pool of the teaching and scientific research base, after 30 days of quarantine breeding observation and random ...

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Abstract

The invention discloses a pelteobagrus fulvidraco mixed bacterium inactivated vaccine. The vaccine comprises the following inactivated antigen compositions: aeromonas sobria inactivated liquid, pseudomonas putida inactivated liquid and plesiomonas shigelloides inactivated liquid in a ratio of 1:1:1, wherein the concentration of the aeromonas sobria inactivated solution is 25 x 10<8> CFU / mL, the concentration of the pseudomonas putida inactivated solution is 25 x 10<8> CFU / mL, and the concentration of the plesiomonas shigelloides inactivated solution is 25 x 10<8> CFU / mL. Antigen components ofthe mixed bacterium inactivated vaccine can generate comprehensive humoral immunity induction on pelteobagrus fulvidraco; and by using the mixed bacterium inactivated vaccine, the immunization frequency can be reduced, the immunization cost is saved, the damage to the pelteobagrus fulvidraco caused by repeated inoculation is reduced, and the application value in actual production is relatively high.

Description

technical field [0001] The invention relates to the technical field of bioengineering, in particular to a mixed bacterial inactivated vaccine of yellow catfish. Background technique [0002] Pelteobagrus fulvidraco belongs to Siluriformes, Paliidae, and Pelteobagrus genus. It is widely distributed in the natural water bodies of rivers and rivers in my country. It has delicious meat, few intermuscular spines, and strong disease resistance. It has become a widely consumed food. It is a famous and high-quality freshwater economic fish that is loved by readers. In recent years, with the continuous expansion of the breeding scale and the continuous improvement of the breeding density, bacterial diseases of the yellow catfish often break out, causing huge economic losses to the farmers and seriously affecting the healthy development of the yellow catfish industry. At present, the main prevention and treatment methods for bacterial diseases of yellow catfish are the use of disinfec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/02A61K39/104A61K39/116A61P31/04
CPCA61K39/104A61K39/025A61P31/04A61K2039/575A61K2039/552A61K2039/542A61K2039/54A61K2039/521A61K2039/70Y02A50/30
Inventor 梁静真盛雪晴杨廷雅魏华杨祖鹏黄钧
Owner GUANGXI UNIV
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