Antidepressant confirmed by pharmacological activity

An antidepressant and pharmacologically active technology, applied in the direction of organic active ingredients, drug combinations, pharmaceutical formulas, etc., can solve problems such as unstable curative effect, series of reactions, damage to liver and kidney function, etc., to improve depression and good safety Effect

Pending Publication Date: 2021-08-24
新疆华春生物药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] At present, most antidepressant drugs are chemical drugs with a wide variety. However, western medicines are often highly dependent, have high toxic and side effects, and are prone to withdrawal symptoms and even a series of reactions, resulting in serious damage to liver and kidney functions, forming a vicious circle. And, treatment Improper use of traditional Chinese med...

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  • Antidepressant confirmed by pharmacological activity

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Comparison scheme
Effect test

Embodiment 1

[0022] An antidepressant confirmed by pharmacological activity, which comprises the following raw materials in parts by weight: 111 parts of polysaccharide extract of Radix Pseudostellariae, 60 parts of total flavonoid extract, and 10 parts of silicon dioxide.

[0023] The preparation method of the antidepressant confirmed by pharmacological activity comprises the following steps: (1) pulverizing the polysaccharide extract of Radix Pseudostellariae Pseudostellariae, total flavonoids extract, and silicon dioxide, and passing through a 60-mesh sieve respectively; (2) pulverizing the above-mentioned pulverized raw materials Mix well and pack into capsules to make.

[0024] In this embodiment, the specific preparation method is:

[0025] (1) The raw materials Pseudostellaria polysaccharide extract, total flavonoid extract, and silicon dioxide are weighed and pulverized, and passed through a 60-mesh sieve to check whether there are foreign objects in appearance;

[0026] (2) Mix t...

Embodiment 2

[0033] The present invention provides an antidepressant drug confirmed by pharmacological activity, which includes the following raw materials in parts by weight: 110.8 parts of polysaccharide extract of heterophylla heterophylla, 59.9 parts of total flavonoid extract, 9.5 parts of silicon dioxide, and the total flavonoid extract It is extracted from kudzu root and epimedium at a ratio of 2:1.

[0034] The preparation method of the antidepressant confirmed by pharmacological activity comprises the following steps: (1) pulverizing the polysaccharide extract of Radix Pseudostellariae Pseudostellariae, total flavonoids extract, and silicon dioxide, and passing through a 60-mesh sieve respectively; (2) pulverizing the above-mentioned pulverized raw materials Mix well and pack into capsules to make.

[0035] In this embodiment, the specific preparation method is:

[0036] (1) The raw materials Pseudostellaria polysaccharide extract, total flavonoid extract, and silicon dioxide are...

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Abstract

The invention provides an antidepressant confirmed by pharmacological activity and a preparation method of the antidepressant. The antidepressant is prepared from the following raw materials in parts by weight: 110 to 111 parts of radix pseudostellariae polysaccharide extract, 59 to 60 parts of general flavone extract and 9 to 10 parts of silicon dioxide. The antidepressant is prepared by mixing a radix pseudostellariae polysaccharide extract, a total flavone extract of radix puerariae and herba epimedii and silicon dioxide. Tests prove that the medicine disclosed by the invention has no withdrawal symptom after the medicine is stopped; the curative effect advantage is realized in the aspect of improving syndromes such as depression and difficulty in falling asleep; and the traditional Chinese medicine composition has more advantages for treating patients with mild and moderate depression, and is relatively good in safety.

Description

technical field [0001] The invention mainly relates to the technical field of medical materials, in particular to an antidepressant confirmed by pharmacological activity. Background technique [0002] Depression is the main clinical feature of significant and persistent low mood, which is the main type of mood disorder; the main manifestations are significant and persistent low mood, depression and pessimism. The mild ones are depressed, unhappy, and lose interest, and the severe ones are overwhelmed with pain, pessimistic and hopeless, living like years, and life is worse than death. The depressed mood of typical patients has a rhythm change that is heavy in the morning and light in the evening; clinically, active speech decreases, the speed of speech is obviously slowed down, the voice is low, and it is difficult to answer. In severe cases, communication cannot be carried out smoothly. In recent years, more and more research data have shown that with the gradual increase ...

Claims

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Application Information

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IPC IPC(8): A61K36/488A61K9/48A61K47/04A61P25/24A61K31/715
CPCA61K31/715A61K36/488A61K36/296A61K9/485A61P25/24
Inventor 胡时先
Owner 新疆华春生物药业股份有限公司
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