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Dihydroquercetin nano-emulsion, and preparation method and application thereof

A technology of dihydroquercetin and nanoemulsion, applied in the field of emulsion, can solve the problems of poor water solubility and low bioavailability of dihydroquercetin

Pending Publication Date: 2021-12-24
蕴能(大连)生物科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] The invention discloses a dihydroquercetin nanoemulsion and its preparation method and application, in order to produce an anti-oxidation nanoemulsion to solve the current shortcomings of poor water solubility and low bioavailability of dihydroquercetin

Method used

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  • Dihydroquercetin nano-emulsion, and preparation method and application thereof
  • Dihydroquercetin nano-emulsion, and preparation method and application thereof

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Embodiment

[0035] The preparation method of following embodiment and comparative example dihydroquercetin nanoemulsion, comprises the steps:

[0036] S1: Divide the water into two parts, add the first part of water and emulsification into the beaker, mix and stir by magnetic stirring at a speed of 1000r / min, and stir for 2 hours to fully hydrate the emulsifier in the first part of water to obtain Emulsifier after hydration;

[0037] Heat the second portion of water to 100°C to obtain boiling water;

[0038] S2: Add dihydroquercetin to the boiling water obtained in step S1 and mix evenly to obtain a dihydroquercetin solution, wherein the particle size of dihydroquercetin is 113.3 nm;

[0039] S3: Add the oil, the post-hydration emulsifier obtained in step S1, and the dihydroquercetin solution obtained in step S2 together into a high-speed disperser for shearing. The speed of the high-speed disperser is 8000r / min, and the reaction time is 3h. The interval is 5s to prepare the primary coa...

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Abstract

The invention discloses a dihydroquercetin nano-emulsion, and a preparation method and application thereof. The dihydroquercetin nano-emulsion is prepared from the following raw materials in parts by weight: 1-20 parts of oil, 1-5 parts of emulsifying agents, 0.01-0.05 part of dihydroquercetin and 80-99 parts of water. The preparation method of the dihydroquercetin nano-emulsion comprises the following steps: S1, dividing water into two parts, mixing and stirring the first part of water and an emulsifier, and heating the second part of water to 100 DEG C to obtain boiled water; S2, preparing a primary crude emulsion; and S3, carrying out homogeneous reaction on the primary crude emulsion obtained in the step S2. The invention also discloses application of the dihydroquercetin nano-emulsion in a food structure modification base material. According to the invention, an antioxidant nano-emulsion is produced, so that the defects of poor water solubility and low bioavailability of the current dihydroquercetin are overcome.

Description

technical field [0001] The invention relates to the field of emulsions, in particular to dihydroquercetin nanoemulsions and a preparation method and application thereof. Background technique [0002] Dihydroquercetin is a dihydroflavonol compound belonging to the vitamin P family and is a widely used bioactive agent. Like other flavonoids, it has a variety of biological activities in the human body, including antioxidant , scavenging free radicals, antiviral, anti-inflammatory, vasodilation and antibacterial effects. At present, there are a large number of dietary supplements using dihydroquercetin, but the solubility of dihydroquercetin in the aqueous phase is not high, which limits its biological activity and reduces its bioavailability. No related emulsion has been found yet product. [0003] In recent years, food-grade nanoemulsions, as a simple and effective embedding transport system, have been widely used in the embedding and delivery of functional oils and various ...

Claims

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Application Information

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IPC IPC(8): A23L33/15A23L29/10A23L29/00
CPCA23L33/15A23L29/10A23L29/03A23V2002/00A23V2250/70A23V2200/222A23V2250/18
Inventor 郑旭于婷穆春旭张树刚关莹
Owner 蕴能(大连)生物科技有限公司
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