Culture method of coenzyme q10 production strain

A culture method and strain technology, which is applied in the cultivation field of coenzyme q10 production strains, can solve the problems of slow growth of strains, failure to meet market demand, low production of coenzyme q10, etc., to achieve accelerated growth and increase production of coenzyme , to maintain the effect of production capacity

Pending Publication Date: 2021-12-28
丽江映华生物药业有限公司
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Problems solved by technology

[0004] At present, the market demand for coenzyme q10 in China is increasing year by year, but when the culture medium used to cultivate coenzyme q10 production strains, the growth

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  • Culture method of coenzyme q10 production strain

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Embodiment Construction

[0041] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention more clear, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments It is a part of embodiments of the present invention, but not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0042] The embodiment of the present invention introduces a culture method for coenzyme q10 production strains, which is used to solve the problem that the growth rate of the strains is slow when the currently used culture medium is cultivating coenzyme q10 production strains, and the strains produced during the fermentation pr...

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Abstract

The invention relates to a culture method of a coenzyme q10 production strain. The culture method of the coenzyme q10 production strain comprises the steps of culture medium preparation, strain purification, mother bottle inoculation, second-stage bottle inoculation and third-stage fermentation bottle inoculation. According to the invention, by improving the formulas of a slant culture medium, a mother bottle culture medium, a seed culture medium and a fermentation culture medium, the growth of the strain can be accelerated, the slow period is short, the strain can be industrially and stably produced on a large scale, the coenzyme production capacity of the strain can be improved, the physiological state is stable, and the stable production capacity is maintained; and a seed expanding process is simplified, and a fermentation process is easier to arrange.

Description

technical field [0001] The invention belongs to the technical field of microbial fermentation, and in particular relates to a method for cultivating coenzyme q10-producing strains. Background technique [0002] Coenzyme q10 (2,3-dimethoxy-5-methyl-6-decenylbenzoquinone, CoenzymeQ10, CoQ10), also known as ubiquinone, decenequinone, widely exists in animals, plants and microorganisms, is a biological An important hydrogen transporter in the cellular respiratory chain. Coenzyme Q10 is an important biochemical drug, which has been widely used in the treatment of various heart diseases, diabetes, cancer, acute and chronic hepatitis, Parkinson's disease and other diseases in recent years. In addition, it also has significant effects in treating scurvy, duodenal ulcer, necrotizing periodontitis, and promoting pancreatic function and secretion. At the same time, coenzyme q10 also has anti-aging effects, and has a wide range of markets in the fields of cosmetics and health products...

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Application Information

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IPC IPC(8): C12N1/38C12P7/66
CPCC12N1/38C12P7/66
Inventor 王钱钢杨晓亮段建海谭志云
Owner 丽江映华生物药业有限公司
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