Construction method of prognosis risk prediction model of early gastric cancer patients

A technology for early gastric cancer and construction methods, applied in the fields of molecular biology and biomedicine, can solve the problems of poor pertinence, single number of genes, and low accuracy, and achieve the effects of reducing influence, high accuracy, and improving prognosis

Pending Publication Date: 2022-02-18
NANJING FIRST HOSPITAL
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  • Claims
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Problems solved by technology

At present, most of the prognostic markers for gastric cancer patients either generally include all patients with TNM stage, which is poorly targeted, or the number of predicted genes is single, and the accuracy is low, which is far from being suitable for the prognosis of early gastric cancer patients. needs

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  • Construction method of prognosis risk prediction model of early gastric cancer patients
  • Construction method of prognosis risk prediction model of early gastric cancer patients
  • Construction method of prognosis risk prediction model of early gastric cancer patients

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Embodiment Construction

[0018] The specific embodiments of the present invention will be further described below in conjunction with the accompanying drawings. It should be noted here that the descriptions of these embodiments are used to help understand the present invention, but are not intended to limit the present invention. In addition, the technical features involved in the various embodiments of the present invention described below may be combined with each other as long as they do not constitute a conflict with each other.

[0019] In describing the present invention, it should be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", " Back", "Left", "Right", "Vertical", "Horizontal", "Top", "Bottom", "Inner", "Outer", "Clockwise", "Counterclockwise", "Axial", The orientation or positional relationship indicated by "radial", "circumferential", etc. is based on the orientation or positional relationship shown in the drawi...

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Abstract

The invention discloses a construction method of a prognosis risk prediction model of early gastric cancer patients. The construction method sequentially comprises the following steps of: S1, data collection; S2, gene and patient prognosis analysis; S3, risk model construction; and S4, risk model accuracy verification. According to the construction method for the prognosis risk prediction model of the early gastric cancer patients, the prognosis prediction model of the early gastric cancer patient is specifically researched, clinical application can be better guided, a more targeted treatment scheme can be provided for the early gastric cancer patients with poor prognosis, precise medical treatment is realized, and the prognosis of the patients is improved; and the number of genes for constructing the prediction model is large, so that the influence caused by tumor heterogeneity can be reduced to the maximum extent, and the accuracy is high.

Description

technical field [0001] The invention belongs to the technical fields of molecular biology and biomedicine, and in particular relates to a method for constructing a prognosis risk prediction model for patients with early gastric cancer. Background technique [0002] Gastric cancer is one of the most common malignant tumors in the world, and its morbidity and mortality are in the forefront of all malignant tumors. The overall survival rate of gastric cancer patients depends on the TNM staging of the tumor. Patients with early gastric cancer undergo surgery and other treatments, and the 5-year survival rate can reach 90%. If it is advanced, the 5-year survival rate of these patients is only about 20%. However, clinically, some patients with early (stage I / II) gastric cancer often have very poor prognosis. Accurately predicting the prognosis of patients with early gastric cancer is of great significance for evaluating and guiding the setting of clinical treatment plans. At pr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/20G16H50/30G16B5/00G16B50/00C12N15/11
CPCG16H50/20G16H50/30G16B5/00G16B50/00
Inventor 王书奎刘翔翔潘玉琴何帮顺秦健孙慧玲许桃
Owner NANJING FIRST HOSPITAL
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