DNA extraction kit based on paramagnetic particle method

Abstract

The DNA extraction kit based on the paramagnetic particle method comprises a kit body, a test tube groove is formed in the kit body and used for containing test tubes, the test tube groove comprises a test tube groove wall and a test tube groove bottom plate, and the test tube groove bottom plate is supported by the lower portion of the test tube groove wall; the test tube groove wall and the test tube groove bottom plate of the test tube groove are respectively connected with a bouncing module of the magnetomotive unit; the magnetomotive unit comprises a bounce module, a central magnetic module and a reset module, and the reset module enables the central magnetic module to reset to an initial position without external force after the central magnetic module rotates forwards and reversely; at the initial position, the mutual exclusion force of the central magnetic module and the bouncing module is smaller than the bouncing sliding resistance of the test tube groove bottom plate and the test tube groove wall; after the central magnetic module rotates, the same part or all of the bouncing modules repel each other, so that the test tube groove bottom plate or the test tube groove wall overcomes resistance to bounce.

Description

technical field [0001] The invention relates to the technical field of a DNA extraction kit based on a magnetic bead method, in particular to a DNA extraction kit based on a magnetic bead method. Background technique [0002] Deoxyribonucleic acid (English DeoxyriboNucleic Acid, abbreviated as DNA) is a kind of nucleic acid, one of the four biological macromolecules contained in biological cells; DNA carries the genetic information necessary for the synthesis of RNA and protein, and is the development and normal operation of organisms. Essential biological macromolecules; DNA is a macromolecular polymer composed of deoxynucleotides; deoxynucleotides are composed of bases, deoxyribose and phosphate; there are 4 kinds of bases: adenine (A), guanine (G), thymine (T) and cytosine (C). In the DNA molecular structure, two polydeoxynucleotide chains are coiled around a common central axis, forming a double helix structure. The deoxyribose-phosphate chain is on the outside of the ...

AI Technical Summary

Problems solved by technology

[0006] Genetic testing will surely become a new symbol of the development of the biology industry. The emergence of high-throughput and automated nucleic acid extraction methods will reduce the human cost of genetic testing and mass testing will become a reality. At the same time, since the discovery of the new crown epidemic, the spread of the new crown epidemic has been rapid , the sudden surge in demand for detection, the use of a large number of DNA extraction kits, hundreds of thousands of levels, or even tens of millions of levels of detection, and the current detection kits are not yet ready for batch operations. The test tubes in the test tube, etc., are used as test samples, which are polluting, dangerous, and contagious

[0007] At present, the existing DNA extraction kit based on the magnetic bead method has a relatively simple structure, basically consisting of a box body and a test tube groove for placing the test tube; because the existing test tube groove is relatively deep, a special tool is required to take the test tube after it is put in. Fixtures are inconvenient; in addition, if the test tube is accidentally broken during the transportation of the kit, it is extremely inconvenient to clean the kit. If it is not cleaned, the spilled medicine will contaminate other test tubes; therefore, how to realize batch unmanned, And cooperate with the automatic operation of the mechanical arm to realize the safe linkage of the test tubes. At present, there is a lack of effective technical means

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