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Traditional Chinese medicine composition for treating acute pancreatitis and application thereof

A technology for acute pancreatitis and its composition, which is applied in the field of traditional Chinese medicine, can solve the problems that patients cannot take traditional Chinese medicine orally, and patients are unwilling to take it as directed, and achieve ideal clinical application effects, safe and effective clinical use, and high trustworthiness

Pending Publication Date: 2022-07-29
FIRST AFFILIATED HOSPITAL OF DALIAN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Patients with pancreatitis are often unable to take traditional Chinese medicine orally due to digestive tract reactions or the need to strictly control the amount of water ingested, and Chinese medicine decoctions are so bitter that most patients are unwilling to take them as directed

Method used

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  • Traditional Chinese medicine composition for treating acute pancreatitis and application thereof
  • Traditional Chinese medicine composition for treating acute pancreatitis and application thereof
  • Traditional Chinese medicine composition for treating acute pancreatitis and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] 1. Materials

[0031] 1.1. Experimental animals

[0032] The SPF grade healthy male adult Sprague Dawley (SD) rats used in this experiment were all purchased from the Experimental Animal Center of Dalian Medical University. Rats weigh 250-280 g. The experimental animals were reared adaptively for 1 week under a 12-hour day-night cycle, the ambient temperature was kept constant at 20-24°C, and the humidity was maintained at 65-70%.

[0033] 1.2. Main reagents and drugs

[0034] Sodium taurocholate was purchased from Beijing Soleibo Company, α-amylase and lipase assay kits were purchased from Nanjing Jiancheng Bioengineering Institute, RNAiso Plus Total RNA extraction kit, Prime Script RT kit, SYBRPremix Ex TaqTM II (Tli RNaseH Plus) was purchased from Akurey Biological Company.

[0035] 2. Method

[0036] 2.1. Preparation of external application of traditional Chinese medicine composition for the treatment of acute pancreatitis

[0037] Turmeric, rhubarb, treats, b...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating acute pancreatitis and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following medicines in mass ratio: 2.5-3.5 parts of rhizoma curcumae longae, 2.5-3.5 parts of rheum officinale, 2.5-3.5 parts of cortex phellodendri, 1-2 parts of rhizoma atractylodis stir-fried with bran, 1-2 parts of cortex magnoliae officinalis, 1-2 parts of pericarpium citri reticulatae, 1-1.5 parts of arisaema cum bile, 2.5-3.5 parts of radix angelicae, 5-6 parts of radix trichosanthis and 1 part of euphorbia kansui processed with vinegar. By adopting the traditional Chinese medicine composition, the symptom of acute pancreatitis can be obviously relieved, the traditional Chinese medicine composition is clinically matched with traditional Chinese medicine and western medicine to treat acute pancreatitis, the effect is ideal, the trouble and pain suffered by a patient can be effectively reduced, the life quality of the patient is improved, and a new treatment way is provided for the patient who cannot orally take traditional Chinese medicine. Therefore, the invention has great significance and wide market prospect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating acute pancreatitis and its application. Background technique [0002] Patients with pancreatitis often cannot take traditional Chinese medicines orally due to digestive tract reactions or the need to strictly control the amount of water intake. Therefore, in recent years, more and more attention has been paid to the study of foreign governance law. The external application of traditional Chinese medicine enables the medicine to be absorbed through the skin and reach the whole body, and the medicine reaches the sick place. This method does not go through gastrointestinal circulation, although the absorption rate may be slightly worse than oral administration, but it is easy to operate and has good patient compliance, especially for patients with severe gastrointestinal reactions. [0003] Ruy...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/06A61P1/18
CPCA61K36/9066A61K36/708A61K36/756A61K36/284A61K36/575A61K36/752A61K36/8884A61K36/232A61K36/428A61K36/47A61K9/06A61K9/0014A61P1/18A61P31/04A61K2300/00Y02A50/30
Inventor 赵亮关溪项红张晓楠周琪于浩
Owner FIRST AFFILIATED HOSPITAL OF DALIAN MEDICAL UNIV
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