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Midicine for resisting tuberculosis and preparation method

A tuberculosis and drug technology, applied in the field of anti-tuberculosis drugs and their preparation, can solve the problems of large expenditure, long course of treatment, allergic reactions and other problems for patients

Inactive Publication Date: 2004-09-15
姚明波
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  • Abstract
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These medicines have obvious disadvantages: one, the course of treatment of these medicines is too long, and the full course of treatment of newly treated smear-negative patients and smear-negative patients needs 6 months, and the full course of treatment of re-treated smear-positive patients needs 8 months; The toxic and side effects are relatively large. Isoniazid and rifampin have toxic and side effects of liver toxicity, gastrointestinal reactions and allergic reactions on average. Pyrazinamide also has toxic and side effects, gastrointestinal reactions, and gouty arthritis. Etamine Alcohol has visual impairment and allergic reactions, and streptomycin has toxic and side effects such as hearing impairment, dizziness, renal dysfunction, and anaphylaxis; 3. Using these drugs for treatment requires a lot of expenses for the patient, and because of the long course of treatment, multiple drugs need to be used in combination , and even use expensive second-line drugs other than the above-mentioned drugs, resulting in excessive expenditure for patients and unbearable

Method used

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Embodiment Construction

[0004] The preparation method and other details of the drug of the present invention will be described in detail below. First, mix dried cantharidin and glutinous rice in a weight ratio of 1:10, and stir-fry in an iron pan until the glutinous rice is brownish-yellow. After cooling, take out the cantharidin and remove the head, feet and wings, crush and sieve (70 mesh) into a concoction. Cantharidum powder. Then open the domestic chicken eggs, remove the yolk, take the pure white juice, and then grind the dried hibiscus leaves into a powder. The traditional Chinese medicine name of the powder is Yulusan. Add the Yulusan to 7 times the weight of boiling water and twist the original juice with gauze. That is, Yulu juice is used as an excipient. In this way, the cantharidin (prince medicine) with strong anti-tuberculosis properties is detoxified by stir-fried glutinous rice (chen medicine), plus the anti-inflammatory and detoxifying effect of Yulu juice (adjuvant), and chicken protein...

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Abstract

The present invention discloses a medicine for curing tuberculous diseases of pulmonary tuberculosis, lymphoid tuberculosis, tuberculosis of spine and intrathoracic tubeculosis and its preparation method. Its main composition comprises (wt%) 1.9512% of mylabris powder, 97.56% of induced protein and 0.04878% of excipient. Its preparation method includes the following steps: placing the mylabris powder into induced protein, uniformly stirring and low-temp. storing, then steaming them, cooling, pulverizing, drying, sieving, adding excipient, making them into small granules, drying.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine, in particular to an anti-tuberculosis medicine and a preparation method thereof. Background technique [0002] In the prior art, my country adopts the chemotherapy regimen recommended by the World Health Organization combined with my country’s practical experience in the treatment of tuberculosis. The main drugs are isoniazid (H), rifampicin (R), and pyrazinamide. (Z), ethambutol (E) or streptomycin (S). These drugs have obvious shortcomings: 1. The treatment course of these drugs is too long. The full course of treatment for newly treated bacteria-positive patients and newly treated smear-yin patients takes 6 months, and the full course of treatment for re-treated smear-yang patients takes 8 months; 2. These drugs The toxic and side effects of isoniazid and rifamp are on average hepatotoxicity, gastrointestinal reactions and allergic reactions. Pyrazinamide also has toxic side...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/17A61P31/06
Inventor 姚明波
Owner 姚明波
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