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Medicine for treating child spasm syndrome and its preparation method

A technology for tics and drugs, applied in drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve problems such as the toxicity of Qing Pinellia, the unsatisfactory effect of patients, and the impact of patients on treatment effects, etc., to achieve Effects of improved neurochemical changes

Active Publication Date: 2007-05-30
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But they still can't achieve the expected satisfactory effect on some patients, and some patients affect the treatment effect because of the side effects of the drug intolerable.
At present, there are also some reports on traditional Chinese medicine. For example, the patent number is 01104315.6. Although it can treat children with tics, its formula contains Chinese medicines of Qing Pinellia and Black Pinellia, and Qing Pinellia is poisonous, and Black Pinellia is a national protected animal.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1-3

[0044] The formulations of Examples 1-3 are shown in Attached Table 1.

[0045] The specific preparation process: extracting Gastrodia elata with 75% ethanol for three times, and recovering the ethanol to obtain extract A; Uncaria and silkworm plus 60% ethanol for refluxing extraction three times, and recovering the ethanol to obtain extract B; First decoct for 1 hour, add three flavors such as Rehmannia glutinosa, decoct three times, filter and mix the three decoction liquids, add ethanol, and recover the ethanol to obtain extract C; after mixing extracts A, B, and C, add steviolin, paste Refine, mix evenly, and then granulate by a spray granulator to make a total of 1000g, which can be divided into packages (6g per bag) to obtain the desired product.

example 4

[0047] This example is the treatment situation of 15 cases extracted from clinical practice in the past ten years.

[0048] (1) Lan XX, male, 9 years old, saw a doctor on September 20, 1990. When she was 5 years old, she was slapped in the face by her father when she was angry and slapped her face because she had slurred her speech while reciting Tang poems. Since then, Xiaolan fell into the problem of blinking, and she kept blinking when she was nervous. A few years later, Xiao Lan's problems continued to worsen. Sometimes she winked, sometimes she shrugged and coughed. She even coughed uncontrollably and made some strange noises in class. She slept less and more dreams, her tongue was normal, her tongue was thin and white, and her pulse was weak. , belongs to the Tourette's Syndrome of the violent panic type, and recovers from illness after taking the medicine for the treatment of tics of the present invention for 5 months. No recurrence was found during the three-year foll...

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PUM

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Abstract

A Chinese medicine in the form of particles for treating the Gilles de la Tourette's syndrome is prepared from 9 Chinese-medicinal materials including prepared rehmannia root, astrodia tuber, Chinese gentian, Dragon's bone, etc. Its preparing process is also disclosed.

Description

technical field [0001] The present invention is a medicine for treating children's tic-tourism syndrome. Background technique [0002] Tourette's syndrome in children is a neuropsychiatric disease that has gradually increased in recent years. Most of the onset is between the ages of 2 and 15. Clinically, it mainly manifests as a muscle in a certain part of the child's body (such as the face, head and neck, limbs, etc.). , or trunk, etc.) involuntary twitching or accompanied by abnormal vocalization of the larynx is characterized by a syndrome characterized by repeated symptoms, such as involuntary blinking, frowning, nose shrugging, mouth opening, head swinging, neck twisting, shoulder movement , shaking hands, raising the abdomen or making a "squeak" sound in the throat, etc. Clinically, most of the patients have kidney yin deficiency, liver wind internal movement type is more common, there is inattention and many small movements. In 1885, French doctor George Gilles de l...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8988A61K36/8888A61K36/804A61K36/74A61K36/515A61K35/56A61K35/02A61K33/26A61K9/16A61P43/00A61K35/586A61K35/64
Inventor 卓金华
Owner JIANGSU KANION PHARMA CO LTD
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