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Antitumor medicine and its production process

A technology of anti-tumor drugs and liquid medicines, which is applied in the direction of anti-tumor drugs, drug combinations, and pharmaceutical formulations, and can solve the problem of ineffective tumor inhibition

Inactive Publication Date: 2005-04-27
SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the existing traditional Chinese medicine antineoplastic drugs are based on strengthening the body, and the effect of inhibiting tumors is not obvious.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] Add 50% ethanol to 4000 g of golden buckwheat and heat to reflux to extract twice, each time for 2 hours, combine the extracts, filter, recover ethanol from the filtrate to obtain medicinal solution A.

[0073] Add 2,800 g of sargassum to decoct with water twice, each time for 2 hours, combine the extracts, and filter to obtain liquid B.

[0074] Combine and concentrate the above medicinal liquids A and B, dry under reduced pressure to obtain a dry extract, and pack into capsules.

[0075] Usage and dosage: Take orally, three times a day, 2 capsules each time.

Embodiment 2

[0077] Add 50% ethanol to 2000 g of golden buckwheat decoction pieces and heat to reflux to extract twice, each time for 2 hours, combine the extracts, filter, recover ethanol from the filtrate to obtain liquid A.

[0078] Add 4000g of sargassum to decoct with water for 2 times, each time for 2 hours, combine the extracts, and filter to obtain liquid B.

[0079] Add 1500 g of Gynostemma pentaphyllum to decoct twice, each time for 2 hours, combine the extracts, filter, concentrate the filtrate to a relative density of 1.10-1.13 (50°C), add 95% ethanol to precipitate with stirring while hot, and let it stand for 24 hours. Suction filtration, recovery of ethanol to obtain liquid C.

[0080] Combine and concentrate the above medicinal liquids A, B, and C, dry under reduced pressure to obtain a dry extract, pulverize, mix with appropriate amount of auxiliary materials, and compress into tablets.

[0081] Usage and dosage: Take it orally, three times a day, 3 capsules each time.

Embodiment 3

[0083] Add 50% ethanol to 3000 g of golden buckwheat decoction pieces and heat to reflux to extract twice, each time for 2 hours, combine the extracts, filter, recover ethanol from the filtrate to obtain liquid A.

[0084] Add 1500g of sargassum to decoct with water for 2 times, each time for 2 hours, combine the extracts, and filter to obtain the medicinal solution B.

[0085] Gynostemma 1000g was decocted twice with water, 2 hours each time, combined the extracts, filtered, and the filtrate was concentrated to a relative density of 1.10-1.13 (50°C), then added 95% ethanol to precipitate with stirring while it was hot, and allowed to stand for 24 hours. Suction filtration, recovery of ethanol to obtain liquid C.

[0086] Add 70% ethanol to 1000 g of seabuckthorn and heat it under reflux to extract twice, each time for 2 hours, combine the extracts, filter, recover ethanol from the filtrate to obtain medicinal solution D.

[0087] Combine and concentrate the above medicinal l...

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Abstract

The present invention is one kind of antitumor medicine and its production process, and belongs to the field of Chinese medicine technology. The antitumor medicine of the present invention has the material including wild buckwheat rhizome and Sarcandrae. The medicine of present invention can inhibit S180 caruncle obviously with tumor inhibiting rate raising with increased dosage and coinciding with the dose-effect relationship, has obtain Lewis lung cancer inhibiting effect, and has obvious immunity strengthening effect. Therefore, the present invention has high antitumor effect and low toxicity.

Description

(1) Technical field [0001] The invention relates to an antitumor drug and a production method thereof, belonging to the technical field of traditional Chinese medicines. (2) Background technology [0002] At present, cancer has become the number one killer of human beings, and lung cancer is one of the common malignant tumors. In recent decades, the incidence and mortality of lung cancer have increased significantly. Traditional Chinese medicine has successful experience and unique advantages in treating cancer, especially non-lethal therapy, which has attracted the attention of the world for its advantages in the treatment of malignant tumors. However, most of the existing traditional Chinese medicine antineoplastic drugs are based on strengthening the body, and the effect of inhibiting tumors is not obvious. The present invention aims at the current situation of anti-tumor traditional Chinese medicine preparations, and researches a traditional Chinese medicine formula wit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P35/00
Inventor 林桂涛牛余珍
Owner SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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