Diffusing-freeing lung rectifying medicinal preparation and its new preparation method

A technology of preparations and traditional Chinese medicine preparations, applied in Tongxuanlifei preparations and new preparation fields, can solve the problems of large dosage, many impurities, and affecting clinical application

Inactive Publication Date: 2006-08-30
FUKANGREN BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in practice, because the medicine is prepared by powdering the medicinal materials into the medicine, there are many impurities and large doses, which seriously affect its clinical application.

Method used

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  • Diffusing-freeing lung rectifying medicinal preparation and its new preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] The preparation method of dropping pill of the present invention:

[0070] prescription:

[0071] Perilla leaves 144g Peucedanum 96g Bellflower 96g Bitter almonds 72g

[0072] Ephedra 96g Licorice 72g Tangerine Peel 96g Pinellia (made) 72g

[0073] Poria cocos 96g Citrus aurantii (fried) 96g Scutellaria baicalensis 96g

[0074] PEG4000 100g

[0075] Makes 1000 pills

[0076] Preparation:

[0077] (1) Take perilla leaves and tangerine peel two medicinal materials, adopt supercritical extraction method: put them into a supercritical extraction tank, extract 3.0h under the conditions of pressure of 20MPa, temperature of 40°C, and flow rate of 20L / h; 5.5MPa, the temperature is 34.5 ℃ (separation I), 34.8 ℃ (separation II) for analysis, to get the extract; The ratio of β-CD is 1:4, sonicate for 30 minutes to obtain clathrate;

[0078] (2) Take the residue after extraction and the remaining medicinal materials in the prescription, add water and decoct 3 times, 1 hour e...

Embodiment 2

[0081] The preparation method of soft capsule of the present invention:

[0082] prescription:

[0083] Perilla leaves 677g Peucedanum 451g Bellflower 451g Bitter almonds 338g

[0084] Ephedra 451g Licorice 338g Chenpi 451g Pinellia (made) 338g

[0085] Poria cocos 451g Citrus aurantium (stir fried) 451g Scutellaria baicalensis 451g

[0086] PEG4000 530g

[0087] Makes 1000 capsules

[0088] Preparation:

[0089] (1) Take perilla leaves and tangerine peel two medicinal materials, adopt supercritical extraction method: put them into a supercritical extraction tank, extract 3.0h under the conditions of pressure of 20MPa, temperature of 40°C, and flow rate of 20L / h; 5.5MPa, the temperature is 34.5 ℃ (separation I), 34.8 ℃ (separation II) for analysis, to get the extract; The ratio of β-CD is 1:4, sonicate for 30 minutes to obtain clathrate;

[0090] (2) Take the residue after extraction and the remaining medicinal materials in the prescription, add water and decoct 3 times...

Embodiment 3

[0093] The preparation method of chewable tablet of the present invention:

[0094] prescription:

[0095] Perilla leaves 238g Peucedanum 158g Bellflower 158g Bitter almonds 119g

[0096] Ephedra 158g Licorice 119g Tangerine Peel 158g Pinellia (made) 119g

[0097] Poria cocos 158g Citrus aurantii (fried) 158g Scutellaria baicalensis 158g

[0098] Makes 1000 pieces

[0099] Preparation:

[0100] (1) get perilla leaf, tangerine peel medical material and powder into medicine;

[0101] (2) Take the remaining medicinal materials from the prescription, add water and decoct 3 times, 1 hour each time, combine the decoction, filter, concentrate the filtrate to a certain volume, add 8 times the amount of 95% ethanol, stir evenly, let stand, and refrigerate 24h, filtered, and the filtrate was concentrated into a thick paste;

[0102] (3) Combine the above active ingredients, add 3.0 g of aspartame and 200.0 g of mannitol, granulate, dry, add 3.0 g of magnesium stearate, mix well, a...

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PUM

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Abstract

A composite Chinese medicine in the form of dripping pill and soft capsule for treating cold cough, fever, headache, sore of limbs, etc, and its preparing process are disclosed.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine composition and a preparation process thereof, in particular to a prescription for cold and cough, fever and aversion to cold, stuffy nose, runny nose, headache without sweating, and sore limbs and the preparation process thereof. Background technique: [0002] Cough, fever, aversion to cold, nasal congestion, runny nose, headache without sweating, and sore limbs are common clinical symptoms. Traditional Chinese medicine often treats them by relieving the exterior and dispelling cold, dispersing the lungs and relieving cough, and the curative effect is remarkable. Tong Xuan Li Fei Wan is its representative drug. However, in practice, because the medicine is prepared by powdering the medicinal materials, it leads to many impurities and large doses, which seriously affects its clinical application. [0003] Compared with ordinary pills, the preparation prepared by the extraction process of the pre...

Claims

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Application Information

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IPC IPC(8): A61K36/8888A61K9/06A61K9/20A61K9/48A61P11/00
Inventor 刘露
Owner FUKANGREN BIO PHARMA
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