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Process for preparing concentration type heat clearing and detoxifying oral liquid

A heat-clearing and detoxifying, oral liquid technology, applied in the directions of medical preparations, pharmaceutical formulations, antiviral agents, etc. containing active ingredients, can solve the problems of low content of active ingredients, inconvenient to carry, unfavorable for patients to take, etc. The effect of increasing the content of ingredients, saving raw materials and packaging materials, and being convenient to take and carry

Active Publication Date: 2007-01-24
河南百年康鑫药业有限公司
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AI Technical Summary

Problems solved by technology

However, the production process of this product is limited by the technical level in the early years. It is only a simple process of water extraction and alcohol precipitation, with many impurities and low extraction utilization rate.
The content of active ingredients in the product is low, resulting in a large dose each time. This large dose is not conducive to children and patients who have difficulty taking medicine. It is also inconvenient to carry. There are still serious drawbacks in the production process.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0014] 1. Take gypsum 67kg, Scrophulariaceae 10.7kg, Rehmannia glutinosa 8kg, Forsythia 6.7kg, Gardenia 6.7kg, Sweet Diding 6.7kg, Gentian 6.7kg, Radix Radix 6.7kg, Anemarrhena 5.4kg and Ophiopogon japonicus 5.4kg, set In the extraction tank, add 900kg of water, heat to 50°C, warm soak for 1 hour, heat to boil, add 13.4kg of honeysuckle and 6.7kg of Scutellaria baicalensis, boil for 1 hour, filter to obtain the filtrate for later use, add 900kg of water to the dregs, and boil for 40 minutes , filtered, combined the secondary extracts, and concentrated to an extract whose measured density was 1.17 at 80°C;

[0015] 2. Add ethanol with a mass concentration of 95% to the extract until the alcohol content of the solution reaches 70%, place it at 10°C for 48 hours, filter, recover the ethanol, and concentrate to a density of 1.30 at 50°C For the extract, add 0.5% active carbon of the extract weight and stir evenly, and heat to 60° C. for 30 minutes, and filter to obtain the filtrat...

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Abstract

The concentrated heat clearing and detoxifying oral liquid is prepared with gypsum, honeysuckle, figwort, rehmannia root, forsythia and other seven kinds of Chinese medicinal materials, and through decocting, filtering, concentrating filtrate to obtain extractum, dissolving in alcohol, filtering and concentrating, adding active carbon, heating and filtering to obtain filtrate, adding water while stirring, ultrafiltering to obtain filtrate, adding corrective and adding water to required concentration, and sterilizing. The concentrated heat clearing and detoxifying oral liquid has relatively high concentration and effective component content, convenient taking and carrying, and other advantages.

Description

1. Technical field [0001] The invention relates to a method for producing oral liquid in the field of medicine, in particular to a preparation method for producing concentrated heat-clearing and detoxifying oral liquid. 2. Background technology [0002] Qingrejiedu oral liquid is a commonly used traditional Chinese medicine preparation, which has the effect of clearing away heat and detoxifying. It is used for those who have fever, flushed face, irritability and drinking, sore throat, flu, and upper respiratory tract infection caused by excessive heat and toxin. It has good clinical effect. Loved by patients. However, the production process of this product is limited by the technical level in the early years. It is only a simple process route of water extraction and alcohol precipitation, with many impurities and low extraction utilization rate. The content of active ingredients in the product is low, resulting in a large dosage each time. This large dose is not conducive...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/08A61K9/10A61P11/04A61P31/16
Inventor 杨士伟蔡俊安王云东郭鑫慧张祥俊鲁张彦
Owner 河南百年康鑫药业有限公司
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