Process for producing maca extract

An extraction method and extract technology, applied in the field of manufacture of maca extract, can solve the problems of no research, concern about anti-allergic effect, etc.

Inactive Publication Date: 2007-02-07
SUNTORY HLDG LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current situation is that the anti-allergic effect is particularly concerned, and there is almost no research on the method of effectively extracting Maca extract with strong anti-allergic effect using a safe solvent.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] Embodiment 1 Manufacture of various Maca extracts

[0059] First, the influence of Maca extraction conditions (extraction temperature, ethanol concentration) on the antiallergic effect of the obtained Maca extract is discussed.

[0060] Get 10g Maca and put into the Erlenmeyer flask of 300ml, add the aqueous solution of each ethanol concentration shown in Table 1 below 100ml, extract 3 hours according to the temperature condition shown in Table 1. Among them, in Invention 10 and Invention 11, Maca was subjected to water extraction at 50° C. for 1 hour in advance, and Maca was used in the residue.

[0061] The extracts obtained above were filtered, and the filtrate was freeze-dried to obtain products 1 to 4 of the present invention. The obtained products of the present invention were formulated into 0.25 mg / ml solutions to evaluate the inhibitory effect of inhibiting the free histamine of the above-mentioned mast cells.

[0062] On the other hand, with respect to the su...

manufacture example 1

[0068] Production Example 1 Pharmaceuticals Containing Maca Extract

[0069] tablet:

[0070] According to the method shown below, a medicine (tablet) containing a Maca extract was produced.

[0071] Take 3 kg of maca dried pulverized material and put it into a stainless steel container, add 30 L of an aqueous solution having an ethanol concentration of 99 volume % therein, and stir at 60° C. for 3 hours. The solution was collected by filtration, and the solvent was removed from the obtained extract to obtain 180 g of Maca extract.

[0072] Get 66.7g of this maca extract, mix with 232.0g of lactose and 1.3g of magnesium stearate, and compress on a single-punch tablet machine to manufacture tablets with a diameter of 10mm and a weight of 300mg.

[0073] Granules:

[0074] 0.5 g of magnesium stearate was added to 99.5 g of Maca extract obtained in the same manner as in the above-mentioned manufacturing example, and granules of 20 to 50 mesh were obtained by compression, crush...

manufacture example 2

[0075] Production Example 2 Various Foods and Drinks Containing Maca Extract

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PUM

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Abstract

The present invention provides an efficient extraction method of Maca extract having safe anti-allergic effects enabling long-term intake, and a food and beverage product, a perfumery and a cosmetic as well as a pharmaceutical preparation comprising thus obtained Maca extract showing anti-allergic effect. In the provided extraction method of Maca extract, the temperature of extracting solution is from 20 DEG C to 75 DEG C when Maca extract is extracted by adding aqueous solution containing ethanol being ethanol concentration of from 20 to 100 by volume%.

Description

technical field [0001] The present invention relates to a method for extracting Maca extract obtained from cruciferous plants, and food, cosmetics or pharmaceuticals containing the extract and having antiallergic effects. Background technique [0002] So far, a large number of compounds with various pharmacological activities have been synthesized, and medicines effective for various diseases have been found and used clinically. Among them, chemically synthesized medicines such as tranilast and cromolyn sodium (hereinafter abbreviated as "DSCG") have appeared as antiallergic agents. In addition, 5-lipid oxygenation agents that generate leukotrienes from arachidonic acid As an enzyme blocker, plant extracts such as mugwort extracts containing a large amount of caffeic acid are used. [0003] However, antiallergic agents generally have side effects such as drowsiness, thirst, and gastrointestinal disorders, and their safety becomes a problem when taken for a long time. On th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K8/97A61K36/31A61Q1/00A23G3/00A23L1/30A61P37/08A23C9/133A23C9/154A23L35/00A61Q1/02A61Q5/02A61Q5/12A61Q7/00A61Q11/00A61Q19/00A61Q90/00C12G3/06
CPCA61K8/97A23C9/133A23C9/1544A23L1/3002A23V2002/00A61Q1/02A61Q5/02A61Q5/12A61Q7/00A61Q11/00A61Q19/00C12G3/06A23L33/105A61K8/9789A61P37/08A61P43/00A23V2200/304A61K36/31A61P27/14
Inventor 加藤惠诹访芳秀福井祐子笹山亚弥松本雄夫
Owner SUNTORY HLDG LTD
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