Biodegradable tissue retractor
a tissue retractor, biodegradable technology, applied in the field of surgical devices, can solve the problems of significant tissue tearing risk, achieve the effect of reducing potential tissue trauma, and reducing the risk of tissue tearing
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[0062] The nature of the invention is clearly demonstrated by an operational example. The technique was used to manipulate the beating heart of a live dog. A primer solution buffered to physiological pH and containing 50 ppm Eosin Y, 0.10 M neutral triethanolamine (TEA) buffer, and 10% of a polymerizable macromer (which contained a polyethylene glycol backbone (3500 MW) with about 5 lactate residues attached, and endcapped with acrylic acid esters) was brushed onto a tissue-affixing article, specifically a 2 cm by 4 cm area of a 2 cm×6 cm polyester (Mersilene™) mesh patch, and also onto the epicardial surface of the LV apex of a beating dog heart that was exposed via thoracotomy. A layer of sealant prepolymer (20% 35,000 MW PEG with trimethylene carbonate linkages and acrylate end caps) also containing Eosin Y and TEA buffer were applied over the primer on the heart. The mesh was placed onto the coated tissue, and a layer of sealant was brushed onto the mesh / tissue surface. Two 20-s...
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