Method and apparatus to insert stoppers into prefilled syringes

a technology of stoppers and syringes, which is applied in the direction of closures using stoppers, liquid handling, packaging goods types, etc., can solve the problems of entrapped air in the syringe and its possible injection into a patient, unfavorable air presence, and particle release by machinery, so as to reduce the movement of machinery parts, improve the process, and reduce the effect of entrapped air

Inactive Publication Date: 2006-08-03
BASCO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0008] It is the purpose of this invention to disclose an apparatus and method for inserting a stopper into a syringe using simplified machinery having less moving parts and that permits a minimum volume of air to remain within the syringe after stopper insertion. In a first embodiment the apparatus provides a stopper insertion system that uses vacuum to assist the insertion of the stopper. This method and apparatus reduces the air entrapped above the liquid in a syringe. A preferred embodiment improves this process by eliminating the stopper ram mechanism and causes insertion of the stopper by controlled use of vacuum. This method and apparatus reduces entrapped air and reduces the moving machinery parts required to insert the stoppers.

Problems solved by technology

The presence of air in the syringe and its possible injection into a patient is undesirable.
This machinery releases particles by wear and interferes with the flow of clean air through the machine.

Method used

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  • Method and apparatus to insert stoppers into prefilled syringes
  • Method and apparatus to insert stoppers into prefilled syringes

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Embodiment Construction

[0015] This first embodiment will be described by referring to FIG. 2. The basic function of this system is the insertion of stoppers 10 (also called pistons or plungers) into filled syringes 12 with vacuum assist. The syringes are filled with a liquid medium 14. The main functional elements for this insertion are stopper tubes 16 and stopper rams 20. The stopper tubes 16 have one or more radial ports 18 which are connected to a vacuum system. A vacuum system, for example, could include a vacuum pump and a vacuum valve. Each functional element is moved relative to each other according to a specific timing. Vacuum supplied by the vacuum system is activated and deactivated according to the stopper tube's 16 and stopper ram's 20 movement. The movements 22 and 24 and timing of stopper tubes 16 and stopper rams 20 are driven for example by mechanical cams, servos, or a robot system. A stopper insertion system can include one stopper tube 16 and stopper ram 20 for sealing one syringe 12 a...

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Abstract

An apparatus and method for inserting a stopper into a medical syringe minimizing the amount of entrapped air between the stopper and the contained liquid. The apparatus in a first embodiment utilizes a vacuum to assist inserting the stopper within the syringe. In a second embodiment a vacuum is used to transport the stopper and cause the insertion into the syringe. This method eliminates a mechanical device that transports the stopper to the syringe.

Description

FIELD OF THE INVENTION [0001] The present invention relates to an apparatus and method for inserting stoppers under a vacuum into a syringe filled with liquid. BACKGROUND OF THE INVENTION [0002] In order to prepare a medical syringe that will be used to inject liquid into a patient, it is critical that the syringe and fluid are free of contamination, biological and chemical. Apparatus used in the process must be made from non-corrosive materials and be located within a controlled atmosphere. Important to the process and apparatus is the prevention of air being retained within the syringe after the filling and stopper insertion processes. The presence of air in the syringe and its possible injection into a patient is undesirable. One of the objectives of syringe filling and closing systems is to minimize the trapped air above the liquid. [0003] The syringes and stoppers are often standardized by the use of ISO (International Organization for Standardization), e.g. ISO 11040-4 and 5 f...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): B65B7/28
CPCB65B3/003B65B7/2821
Inventor GRIEBEL, ROBERT ANDREE EMILRINK, MARKUSMANZ, STEFANSTROETER, BERNDBAUSCH, ERNST WILHELM
Owner BASCO TECH
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