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Rapid and Accurate Detection of Bone Quality Using Ultrasound Critical Angle Reflectometry

a critical angle reflectometry and rapid detection technology, applied in the field of bone quality determination, can solve the problems of recurrent fractures that do not heal properly, severe impairment of bone quality, and inability to detect inferior bone quality, so as to reduce bone quality and detect inferior bone quality

Inactive Publication Date: 2010-05-06
BOARD OF RGT THE UNIV OF TEXAS SYST
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

Enables precise, automated, and non-invasive measurement of bone elasticity and anisotropy, effectively tracking changes in bone quality during treatments, such as bisphosphonate therapy, and identifying patients at risk for fractures.

Problems solved by technology

Osteoporosis is a major medical problem, with a large percentage of elderly persons being susceptible to sustain non-traumatic fractures (bone fractures from minimum trauma).
Recent discoveries, however, have presented situations in which severe impairment of bone quality can occur.
With long-term use, new studies suggest that these drugs can severely impair bone quality, leading to recurrent fractures that do not heal properly (Ott, J. Clin. Endo. Metab.
These patients are known to have increased susceptibility to fractures, since they probably have defective bone from taking steroids and suffer from other factors that are harmful to bone.

Method used

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  • Rapid and Accurate Detection of Bone Quality Using Ultrasound Critical Angle Reflectometry
  • Rapid and Accurate Detection of Bone Quality Using Ultrasound Critical Angle Reflectometry
  • Rapid and Accurate Detection of Bone Quality Using Ultrasound Critical Angle Reflectometry

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Embodiment Construction

[0035]While the making and using of various embodiments of the present invention are discussed in detail below, it should be appreciated that the present invention provides many applicable inventive concepts which can be embodied in a wide variety of specific contexts. The specific embodiments discussed herein are merely illustrative of specific ways to make and use the invention and do not delimit the scope of the invention.

[0036]Ultrasound Critical Angle Reflectometry (UCR). In the early 1990s, the present inventors introduced a novel method, called ultrasound critical angle reflectometry or UCR, for measuring bone quality based on the “reflection” of ultrasound across small parts of bone surfaces of about 0.2 mm (Antich, et al., J. Bone Min. Res. 6:417-426, 1991). Bone quality may be derived or inferred from ultrasound velocity. The original UCR device determined velocity in cortical bone (“hard bone” on outer parts of bone tissue) as well as in trabecular bone (“spongy bone” in ...

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Abstract

The present invention is an apparatus, method and system for determining the coefficient of elasticity of a target by detecting an ultracritical reflection of ultrasound waves directed at the target using an ultrasound transducer at two or more angles simultaneously and calculating the elasticity coefficient of the target.

Description

CROSS-REFERENCE TO RELATED APPLICATION[0001]This application claims priority to provisional patent application Ser. No. 60 / 487,334, filed Jul. 15, 2003, and co-pending U.S. patent application Ser. No. 10 / 630,330 filed Jul. 30, 2003, to issue as U.S. Pat. No. 7,611,465 on Nov. 3, 2009.TECHNICAL FIELD OF THE INVENTION[0002]The present invention relates in general to the field of bone quality determination, and more particularly, to the rapid and accurate measurement of elasticity coefficients, in vivo of cortical and trabecular bone.BACKGROUND OF THE INVENTION[0003]Without limiting the scope of the invention, its background is described in connection with bone density measurements, as an example.[0004]Need for Non-Invasive Measurement of Bone Quality. Osteoporosis is a major medical problem, with a large percentage of elderly persons being susceptible to sustain non-traumatic fractures (bone fractures from minimum trauma). Bone strength is a primary predictor of bone fractures. Bone s...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61B8/00A61B8/08
CPCA61B5/0048A61B8/0875A61B8/485
Inventor ANTICH, PIETROPAK, CHARLES Y.C.SMITH, BILLYRICHER, EDMONDLEWIS, MATTHEW A.
Owner BOARD OF RGT THE UNIV OF TEXAS SYST
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