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Cosmetic use of botulinum toxin for the treatment of eyebrow and forehead ptosis, and unwanted eyebrow expression

The microdroplet injection technique for botulinum toxin between the skin and orbicularis oculi muscle addresses the issue of unwanted side effects in treating eyebrow ptosis and expression by selectively weakening eyebrow depressor muscles, achieving effective eyebrow elevation and reduced risk of eyelid ptosis.

Inactive Publication Date: 2011-11-17
STEINSAPIR KENNETH D
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This method effectively elevates the eyebrow position and softens glabellar muscle activity without inducing upper eyelid ptosis, allowing for a more desirable appearance by selectively weakening the orbicularis oculi and other contributing muscles, while minimizing the risk of toxin diffusion.

Problems solved by technology

Aesthetically this change makes the eyes look small and is not desirable.
This technique is limited by fear of inducing the undesired side effect of ptosis of the upper eyelid, where the upper eyelid droops causing visual obstruction.

Method used

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Embodiment Construction

[0019]Botulinum toxin is a general term for any of the neurotoxins produced by any of the members the bacterial organisms that belong to the Clostridium botulinum species. Fourteen pathogenic strains of this species have been isolated from botulism outbreaks in humans and animals. These organisms have been shown to produce seven immunologically distinct types of neurotoxin (types A, B, C, D, E, F, and G). The term “BTX” is used to refer to this family of neurotoxins. Currently only botulinum toxin types A and B are commercially available for clinical use: Botulinum toxin A from Allergan Inc., Irvine, Calif., under the trade name BOTOX®, and from Ipsen Ltd., Slough, UK, under the trade name Dysport® and Reloxin®. Botulinum toxin B is available from Solstice Neurosciences, Inc, South San Francisco, Calif., under the trade name Myobloc®.

[0020]The treatment dose of BTX is measured in “Unit” equivalents, which is defined on the basis of a biological assay. One Unit equivalent is defined ...

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Abstract

A method of temporarily elevating the eyebrow position and softening undesirable glabellar muscle activity to affect a more desirable appearance. In a broad aspect the invention comprises injecting small quantities of botulinum toxin (BTX) dissolved in microdroplets of injectable saline carrier to treat the septal and orbital orbicularis oculi muscles, on each side of a patient's face. In sufficient numbers, injected microdroplets of BTX are able to selectively weaken these muscles. This method preferably also includes using microdroplets of BTX to treat: a) the depressor supercilii muscle, on each side; b) the procerus muscle; c) the corrugator supercilii muscle, on each side; and d) the inferior limit of the frontalis muscle where it meets the superior aspect of the orbital portion of the orbicularis oculi muscle.

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]This is a continuation of U.S. Ser. No. 11 / 429,057 entitled “Cosmetic Use of Botulinum Toxin for the Treatment of Eyebrow and Forehead Ptosis, and Unwanted Eyebrow Expression”, filed May 4, 2006. The content of U.S. Ser. No. 11 / 429,057 is incorporated by reference herein in its entirety.BACKGROUND OF THE INVENTION[0002]1. Field of the Invention[0003]The present invention relates generally to the cosmetic use of neurotoxin agents and more particularly to an improved method for injecting botulinum toxin (BTX).[0004]2. Description of the Related Art[0005]The position and appearance of the eyebrows is determined at rest and dynamically by the opposing action of several groups of muscles that act on the eyebrow. The frontalis muscle primarily performs eyebrow elevation. Brow elevation is opposed by the septal and orbital portions of the orbicularis oculi muscle, including the depressor supercilii component of the orbicularis oculi muscle, and ...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K38/16A61Q90/00
CPCA61K8/64C12Y304/24069A61K38/4893A61Q19/08Y02A50/30
Owner STEINSAPIR KENNETH D
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