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Oral Care Compositions and Methods of Use

Inactive Publication Date: 2018-06-07
COLGATE PALMOLIVE CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The patent text describes how certain ingredients in dentifrices with hydrogen peroxide can reduce or eliminate the production of gas during use. This helps to make the dental product more stable and of higher quality, which can improve its shelf-life.

Problems solved by technology

Many individuals desire a “bright” smile and white teeth, and consider dull and stained teeth cosmetically unattractive.
However, peroxide compounds are highly reactive, and consequently difficult to formulate.
The off-gas accumulation can be problematic as in storage, dentifrice containers may bloat, burst or leak, and the remaining formulation will not have enough peroxide remaining to clean and whiten teeth effectively.
Current oral care market products do not adequately address off-gassing resulting from hydrogen peroxide decomposition.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

d Caliper Assessment of Peroxide Formulated Dentifrices

[0059]Dentifrice off-gas production was evaluated on tubes (Catalog #, Company) filled with test dentifrice formulations and measured using a digital caliper and visual observance. Visual observance focused on bloating, open crimping or open cap. The digital caliper was used to measure changes in tubular width. Filled tubes were incubated at either 40° C. and at 75% relative humidity, 49° C. or 60° C. Complete burst rates for the formulations containing an off gas reducing agent was observed up to 20 weeks, as compared to 12 weeks for the formulation not containing a select off gas reducing agent (Example A). Further, an increase of 33% in tubular width was observed at up to 13-14 weeks when an off-gas reducing agent was present compared to 9-10 weeks for the control group (Example A).

TABLE 1FormulationIngredientExample AExample BExample CExample DExample EPropylene Glycol39.9139.8639.8639.8639.86Polyethylene Glycol / Propylene 10...

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Abstract

Disclosed herein are non-aqueous dentifrice compositions comprising (i) a whitening complex comprising crosslinked polyvinylpyrrolidone complexed with hydrogen peroxide; (ii) an off-gas reducing agent selected from sodium sulfate, magnesium sulfate, citric acid and clay; and (iii) an orally acceptable carrier. Methods of making and using the compositions are also provided.

Description

FIELD[0001]This invention relates to non-aqueous hydrogen peroxide containing oral care compositions having reduced off-gassing effects as well as to methods of using and of making these compositions.BACKGROUND[0002]Many individuals desire a “bright” smile and white teeth, and consider dull and stained teeth cosmetically unattractive. Thus, there is a desire for whiter teeth and one means to achieve whiter teeth is the use of tooth whitening products.[0003]Teeth can become discolored by foods, drinks and tobacco use. Dental stains can be classified as either extrinsic, which occur on the outer surface of teeth, or intrinsic, which occur below the surface of enamel. Most abrasive containing toothpaste remove extrinsic stains. Hydrogen peroxide (H2O2) can bleach both extrinsic and intrinsic stains and so provides fast and superior whitening efficacy. The peroxide can bleach the teeth, remove stains, and kill cariogenic bacteria. However, peroxide compounds are highly reactive, and con...

Claims

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Application Information

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IPC IPC(8): A61K8/22A61K8/23A61K8/27A61K8/25A61Q11/02
CPCA61K8/22A61K8/23A61Q11/02A61K8/25A61K8/27A61K8/365A61Q11/00A61K8/8182A61K2800/31
Inventor NESTA, JASONPILCH, SHIRA
Owner COLGATE PALMOLIVE CO