Methods and systems for enhancing safety of psychedelic drug therapies
a psychedelic drug and safety technology, applied in the field of methods and systems for enhancing the safety of psychedelic drug therapies, can solve the problems of unfulfilled elucidation of risks associated with the chronic use of psychedelic compounds, the precipitation of psychosis, hypomania, or mania, and the clinical risk associated with the therapeutic application of psychedelic, dissociative and empathogenic compounds, etc., to achieve enhanced patient safety and enhance patient safety in the therapeutic regimen
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example 1
a Psilocybin Therapy Patient for Risk of Developing Psychosis
[0182]A 35-year old patient diagnosed with major depression has scored 17 on the 29-item Hamilton Rating Scale for Depression (HRSD) and is identified as a candidate for a complex therapy featuring in-patient administration of psilocybin in combination with adjunctive behavior therapy. Utilizing a mobile device operated by a clinician responsible for screening patients for eligibility to receive the complex therapy, the patient is instructed to describe a recent dream they have had, or to react to an image or photograph known to elicit a negative emotional response, and this response is recorded, pre-processed, and transmitted via the mobile device to a remote server for analysis. Alternatively, this assessment is conducted remotely by a screening clinician via computer or mobile device, or via an automated screening application delivered via computer or mobile device. The patient is notified by the screening clinician dur...
example 2
Safety Monitoring of LSD Therapy Patient for Risk of Developing Psychosis
[0184]After agreeing to adhere to a smartphone-based screening program as a follow-on component of the complex therapy involving LSD and behavior therapy, a 54-year old patient diagnosed with substance abuse is administered LSD at a treatment center. The patient downloads a software application to her smartphone at the treatment center, is instructed on the proper and regular use of the application, and is notified via push notifications when her mobile device safety session is scheduled, e.g., monthly, beginning one day after the complex therapy is administered.
[0185]Utilizing the smartphone-based safety monitoring application, the patient is digitally prompted to speak freely about a recent experience and her expectations for the future. Several follow-on prompts are provided to generate a twenty-minute audio recording, which is pre-processed on the smartphone processor and sent to a remote server for languag...
example 3
t Administration of R-DOI for Acute Inflammatory Condition
[0187]A 65-year old patient is diagnosed with herpetic encephalitis, is hospitalized due to the life-threatening nature of the condition, and requires immediate treatment with anti-inflammatory therapy. Following administration of R-DOI, the patient's encephalitis is successfully treated and he is evaluated by doctors for release from the hospital. Utilizing a mobile device operated by clinicians at the hospital, clinicians instruct the patient to describe a recent dream he has had, or to react to an image or photograph known to elicit a negative emotional response, and capture his response via the mobile device for pre-processing and transmission to a remote server for analysis. Using methods described herein, the remote server determines that the patient is at low risk for developing psychosis, hypomania, or mania and is released from the hospital once this result is transmitted back to supervising clinicians at the hospita...
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