32results about How to "Avoid gastrointestinal irritation" patented technology

The invention relates to a traditional Chinese medicine gel for treating arthritis and preparation method thereof, belonging to medical field. The gel is composed of raw sihcuan axonite root extract and pharmaceutical adjuvant by the following weight ratio: raw sihcuan axonite root extract 1.5%, camphor 0.1%, musk 0.04%, high molecular matrix material 0.1-5%, humectant 5-15%, preservatives 0-0.5%, solvent 50-80%.

The invention provides a Chinese medicine composition to achieve the purpose of treating senile vaginitis through dispelling wind, arresting itching, removing dampness, and destroying parasites. In order to achieve the purpose, the following technical scheme is adopted: active components contained in the Chinese medicine composition are prepared by the following raw materials in parts by weight: 10-20 parts of radix stemonae, 10-20 parts of semen armeniacae amarae, 10-20 parts of chinaberry seeds, 10-20 parts of lindley eupatorium, 10-20 parts of patrinia heterophylla, 10-20 parts of oroxylum indicum, 10-20 parts of polygonum cuspidatum, 1-3 parts of borneol, 1-3 parts of carbomer, 50-100 parts of glycerol, 1-3 parts of triethanolamine and 425-475 parts of distilled water; and the raw materials are prepared into gel by adopting a corresponding preparation method. The Chinese medicine composition has the functions of dispelling wind, arresting itching, removing dampness, and destroying parasites, and can be used for treating the senile vaginitis.

The invention relates to medicinal liquor and particularly relates to externally applied medicinal liquor for treating lumbar and leg ache. The externally applied medicinal liquor for treating lumbar and leg ache is prepared by soaking asarum, liquidambar formosana hance, angelica sinensis, frankincense, radix aconiti, caulis spatholobi, fructus aurantii, rheum officinale, peach kernels, radix clematidis, flos carthami, myrrh, cassia twig, dandelion, salviae miltiorrhizae, hematoxylon, scandent schefflera stems and leaves and borneol in wine, wherein asarum contains volatile oil which has the antipyretic and antinociceptive effects; liquidambar formosana hance contains sanchinoside which has the effects of promoting blood circulation to remove blood stasis, relieving swelling and pain and dredging channels and stopping bleeding; angelica sinensis, frankincense, radix aconiti, caulis spatholobi, salviae miltiorrhizae and the like have the functions of promoting circulation of blood, invigorating the circulation of blood and relieving pains; borneol is led to the apertures to assist the medicines to directly reach the diseased regions.

The present invention belongs to the field of Chinese medicine technology, and is especially one kind of compounding Chinese gel preparation for treating osteoarthropathy and its preparation process. The Chinese gel preparation consists of raw aconite root extractive, datura flower extractive, camphor, musk, polymer as matrix, solvent, humectant, preservative and other supplementary material. Compared with available technology, the Chinese gel preparation for transdermal administration of the present invention has no irritation to gastrointestinal tract, lowered body blood medicine concentration, reduced toxic side effect, prolonged acting period, raised patient compliance to the medicine, easy use and low cost.

The present invention relates to tromethamine gel with tromethamine as effective non-steroid medicine component for relieving pain and diminishing inflammation caused by surgical operation, fracture, strain, cancer, etc. through skin, mucous membrane or other local application, and aims at raising the long term stability, raising the bioavailability of the medicine component, reducing stimulation and raising the curative effect and medicine applying safety. The final medicine composition contains tromethamine 0.5-2.0 wt%, gel matrix 0.1-1.0 wt%, transdermal absorbent 0.2-2.0 wt%, humectant 0.2-2.0 wt%, and pH buffering agent 0.3-1.5 wt%. It is preparation through convenient gel preparing process.

The present invention relates to one kind of release controlling microcapsule preparation for preventing abdominal cavity carcinomatosis and its abdominal cavity infusing application technology. The release controlling microcapsule preparation is infused into abdominal cavity after cancer tissue incising operation and the medicine is released timely to prevent carcinomatosis and inhibit the growth of cancer cells. Technologically, the present invention includes three key aspects: preparing release controlling microcapsule, selecting proper solvent and abdominal cavity infusion technology. By means of the technology of combining release controlling microcapsule and abdominal cavity infusion, the present invention has high medicine bioavailability.

The invention relates to a novel gynecological Qianjin zedoary turmeric oil suppository. The preparation method comprises the following steps: (1) taking raw materials: radix flemingiae macrophyllae, radix rosae laevigatae, caulis mahoniae, caulis spatholobi, radix zanthoxylum echinocarpum, herba andrographis, radix codonopsis, radix angelicae sinensis and zedoary turmeric oil; (2) preparing extractives; (3) heating and melting polyethylene glycol 6000 and poloxamer 188 in water bath, adding tween-80, the zedoary turmeric oil and extractives, stirring evenly and fully, keeping warm, pouring into a suppository mold coated with liquid paraffin on the surface, and obtaining the Qianjin zedoary turmeric oil suppository after cooling. According to the novel gynecological Qianjin zedoary turmeric oil suppository, drug parts of gynecological Qianjin capsules are integrated with the zedoary turmeric oil to prepare the suppository, plugging the suppository into a vaginal can treat vaginitis and cervicitis; plugging the suppository into a rectum can treat dysmenorrhea, amenorrhea, soreness of waist, annexitis, endometritis, chronic pelvic inflammatory disease and the like, and the suppository can also be used in a menstrual period. Rectal blood circulation is very rich, the drug does not pass through an upper gastrointestinal tract after the suppository is used, gastrointestinal irritation is avoided, the drug can be quickly absorbed to reach a pelvic cavity and plays a therapeutic effect, and obvious toxic and side effects are avoided.

The invention discloses a pharmaceutical composition as well as a preparation method and application thereof. The pharmaceutical composition comprises bepotastine besilate, a tackifier, a tension agent, a preservative and a pH regulator, wherein the granularity D90 of the bepotastine besilate is 2-10 [mu]m. The preparation method of the pharmaceutical composition comprises the following steps of (1) pre-treating the bepotastine besilate; and (2) preparing the pharmaceutical composition. The preparation method is simple and easy to implement, and the prepared pharmaceutical composition enters the nasal cavity through a portable spraying device, is convenient to administrate, takes effect quickly, can release drugs slowly, is high in bioavailability, stable in product quality and small in irritation to the nasal cavity, and can be used as an antihistamine drug.

The invention discloses an external application formula for herpes zoster to solve the problem of treatment of herpes zoster. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 1-5 parts of paris polyphylla, 1-5 parts of hibiscus mutabilis, 1-5 parts of cyrtomium fortunei, 1-5 parts of cortex pseudolaricis, 1-5 parts of wild buckwheat rhizome, 3-5 parts of prepared frankincense, 3-5 parts of prepared myrrh, 5-10 parts of golden cypress, 5-10 parts of coptis chinensis and 5-10 parts of rheum officinale. Clinical results prove that the composition for treating herpes zoster has the characteristics of good curative effect and higher safety, and is worthy of clinical application and popularization.

The invention discloses a local medicine preparation with cinacalcet. The local medicine preparation comprises the following components: 1% of cinacalcet, 0-10% of a penetrant, 0-20% of a solvent and84-94% of a matrix. The local medicine preparation with the cinacalcet is prepared by dissolving the cinacalcet, the penetrant and the matrix into the solvent, heating the components to 55 DEG C, stirring and mixing the components, and cooling the mixture to the room temperature. By adopting a local drug delivery mode, gastrointestinal tract irritation caused by orally taken medicines can be avoided, a high medicine concentration can be maintained in local action tissue, the treatment effect can be improved, side reactions of a whole body can be avoided, and remarkable clinical advantages canbe achieved.

The invention provides a traditional Chinese medicinal preparation for treating prostatitis and a preparation method thereof. The traditional Chinese medicinal preparation is prepared from the following raw medicinal materials in parts by weight: 10-20 parts of cowherb seed, 10-20 parts of tabasheer, 10-20 parts of polygonum cuspidatum, 10-20 parts of myrrh, 10-20 parts of rhizoma bolbostemmae, 10-20 parts of sharpleaf galangal fruit and 1-10 parts of nidus vespae. The preparation has the advantages of high bioavailability and good treatment effect.

The invention relates to medicinal liquor and especially relates to and discloses externally-used medicinal liquor for treating ischemic heart disease. The medicinal liquor is prepared by soaking medicines including monkshood, cinnamon, achyranthes bidentata, gentiana macrophylla, mulberry twigs, aconitum gymnandrum, angelica pubescens, red peony roots, uncaria tomentosa, scorpions, bombyx batryticatus, earthworm, fresh ginger and radix glycyrrhizae in liquor. According to traditional Chinese medicine theories, the medicinal liquor is prepared through a combination formula according to relationships among monarch drugs, minister drugs, assistant drugs and guide drugs on the basis of functions of the medicines so that the effects of the medicines can be achieved in a cooperation manner. The medicinal liquor has main effects of freeing yang and opening paralysis and freeing collaterals and relieving pains and is mainly used for treating acute myocardial infarction, unstable angina pectoris and the like.