The invention belongs to the technical field of chess game devices, and relates to an infant three-dimensional chess containing a filler. A body structure of the three-dimensional chess is provided with a base, the filler and a top structure, the interior of the base is of an internally-controlled cavity structure, the cavity is filled with the filler, the bottom of the base is connected with a base plate through threads or buckles. The top structure is designed into different shapes according to different chess pieces; the commander, the bodyguard, the elephant, the horse, the vehicle, the cannon and the soldier in the chess pieces respectively select any one of plant seeds such as wheat, rice and the like or mineral particles to be filled in the cavity of the base. Development of intelligence of infants and children is facilitated, and learning interest is improved; the cavity can be opened, so that a user can conveniently see seeds or mineral substances and know natural substances while playing chess for entertainment, and love for life is enhanced; and a good habit of loving labor and cherishing grains is formed.