115results about How to "Lower uric acid" patented technology

The invention discloses 2-(3-cyano-4-isobutoxy phenyl)-4-methyl-5-thiazolyl formic acid of a new delta-crystal form and a preparation method thereof. The method comprises the steps of: heating a mixture of Febuxostat and absolute ethanol till completely dissolving, and then filtering to obtain an alcoholate; putting the alcoholate in a 80 DEG C baking oven for baking for 2 hours under 2mmHg vacuum decompression to obtain crystals of the delta-crystal form, which has excellent temperature and humidity stability, no any organic solvents or water and is suitable for preparation process and long-term storage. A medicine composite which takes the compound of the crystal form can be used for reducing uric acid in blood and treating all clinical hyperlithic situations, such as uarthritis.

The invention relates to medicinal and edible tablets for reducing uric acid and a preparation method of the medicinal and edible tablets. The medicinal and edible tablets comprise a main constituentand an auxiliary material, wherein the main constituent comprises components in parts by weight as follows: 0.33 g of cichorium intybus powder, 0.01 g of fructus gardeniae powder, 0.01 g of folium mori, 0.01 g of radix puerariae, 0.01 g of rhizoma smilacis glabrae and 0.08 g of celery seeds, and the auxiliary material comprises components of 0.04 g of curcumin, 0.014 g of maltodextrin, 0.012 g ofvegetable fat powder, 0.002 g of magnesium stearate, 0.05 ml of palm oil and 0.05 ml of vegetable oil. The medicinal and edible tablets taste good, the preparation method is simple and practicable, and wide popularization can be facilitated; the medicinal and edible tablets have obvious effect, are high in pertinence and convenient to take and store and do not affect blood pressure, blood sugar and blood fat, and the preparation method is simple and practicable.

The invention relates to uric acid-lowering marine fish oligopeptide and a preparation method thereof. According to the preparation method, marine fish is taken as a raw material, the fish meat of themarine fish is treated by using methods such as a steam explosion treatment method, a protease enzymolysis method and a microbial fermentation method, and desalting treatment is carried out by combining ultrasonic waves with a membrane separation technique, so that the uric acid-lowering marine fish oligopeptide product can be finally obtained; the obtained acid-lowering marine fish oligopeptideproduct is stable in properties, high in contents of active components and low in salt content, has effects of reducing uric acid, improving endurance, relieving muscle pain and the like, can be matched with euglena for use, is also used as a food additive, a raw material for health care products and the like, has a high economic value, and is suitable for large-scale industrialized production.

The invention provides healthcare medicinal liquor, which is prepared from high-quality white spirit that is brewed from pure sorghum in which more than 30 rare Chinese herbal medicines are soaked for the number of whole days. The healthcare medicinal liquor is suitable for industrial mass production; repeated clinical practices for decades show that the medicinal liquor has double-insurance effect on people with kidney essence, yin and yang deficiency as well as mental deficiency, and is capable of treating all diseases caused by kidney essence, yin and yang deficiency; in addition, the medicinal liquor has a prevention function, complies with traditional Chinese medicine habit of preventive treatment of disease. The medicinal liquor has excellent effect and is popular with patients.

The invention relates to an application of herba lysimachiae total flavonoids in preparation of a medicine for relieving hyperuricemia. The content of total flavonoids in the herba lysimachiae total flavonoids is more than 60%, and the herba lysimachiae total flavonoids contain 7.0wt% to 10.0wt% of kaempferol, 6.0wt% to 9.0wt% of quercetin, 5.0wt% to 9.0wt% of rutin, 7wt% to 10wt% of epicatechin and 7.0wt% to 10wt% of hesperidin. The herba lysimachiae total flavonoids are high in total flavonoid content and definite in ingredients, and also have the function of obviously lowering serum uric acid of a model rat with the hyperuricemia under the condition of the total flavonoids in a low dose, so that the herba lysimachiae total flavonoids are high in safety and are of a good medicine for lowering high uric acid and treating gout. In addition, the herba lysimachiae total flavonoids are simple in preparation process and are suitable for industrial production and applications.

The invention relates to the technical field of enzyme preparation, in particular to comprehensive enzyme powder with a lipolysis function and a preparation method of the comprehensive enzyme powder with the lipolysis function. The comprehensive enzyme powder is prepared from, by weight, 1-5 parts of compound decomposition enzyme, 10-30 parts of natto, 50-70 parts of vegetables, 80-100 parts of fruits, 10-30 parts of edible fungi, 10-15 parts of medicinal and edible traditional Chinese medicine extracts, 5-10 parts of mushroom extracting liquid and 40-80 parts of pineapple powder by addition of enzyme strains. Compared with the prior art, the comprehensive enzyme powder with the lipolysis function has the advantages of diversity, balance and easiness in absorption. The preparation method has the advantages that fungal polysaccharides are extracted through combination of ultrasonic waves and an enzymolysis method, fungal cell wall crushing effects are enhanced by ultrasonic waves to increase polysaccharide dissolution rate, cell walls are subjected to further enzymolysis by the enzymolysis method to enable intercellular polysaccharides to be released sufficiently, and accordingly the preparation method is efficient, time saving, labor saving, higher in polysaccharide yield and purity and suitable for large-scale production and application.

The invention discloses a kelp-amino composite tablet for lowering content of uric acid and a preparation method thereof. The composite tablet comprises a kelp extract, a nutrient with amino and vitamin C in a weight ratio of 1:(0.5-1.5):(0.5-1.5). The preparation method of the composite tablet comprises the following steps of: (1), preparing the kelp extract: adding 1000kg (based on wet weight) of the kelps and seawater of 80-90 DEG C into a large steaming pot for one minute, cooling the seawater after taking out the kelps, adding neutral potassium salt which accounts for 20%-60% of the wet kelps, salting for 24 hours, centrifuging by a centrifugal machine to obtain 300 L of liquid containing the kelp extract, and then adding water and alcohol to precipitate to obtain the kelp extract; (2), adding the nutrient with the amino into the kelp extract prepared in the step (1); (3), adding vitamin C and pressing into the composite sugar tablet. The composite tablet disclosed by the invention is simple in extracting process and concise in synthesis. The product is synthesized by pure natural food, free of side effect and obvious in effect for lowering uric acid.

The present invention discloses uric acid-lowering flavored black tea drink. The uric acid-lowering flavored black tea drink is mainly composed of glutinous Fuzhuan tea, Liupu tea, Pu'er cooked tea, floral-type black tea, lotus leaves and cyclocarya paliurus as raw materials. After extraction, lemon slices, Kunlun snow chrysanthemum, honeysuckle, a grosvenor momordica fruit extract and a stevioside extract are added for seasoning, and filtering and sterilizing are conducted to prepare the finished product. The black tea, lotus leaves, cyclocarya paliurus and honeysuckle are combined, so that the tea drink has the effects of lowering uric acid, clearing heat and removing toxins; the floral-type black tea, lemon slices and Kunlun snow chrysanthemum are added to enhance the flavor and aroma of the drink; and the grosvenor momordica fruit extract, stevioside extract and other low-calorie plant source sweeteners are added to regulate the mouthfeel of the drink, so that the drink flavor is more accepted by the public, and also satisfies the public's pursuit of low-sugar and low-calorie tea drink products.

The present invention discloses a composition for promoting uric acid reduction. The composition comprises the following components in parts by weight: 10-25 parts of poria cocos, 10-25 parts of coixseeds, 10-20 parts of kudzuvine roots, 7-14 parts of psyllium seed husk powder, 8-16 parts of chia seed powder, 0.5-3 parts of skipjack elastin and 100 parts of auxiliary materials. The composition has the synergistic effect in a plurality of aspects such as reducing blood sugar, blood fat and cholesterol, promoting uric acid excretion, promoting the balance of ion metabolism of the body and promoting the balance of sputum metabolism, thereby jointly inhibiting the production of uric acid, increasing the excretion of uric acid and promoting the reduction of uric acid. The present invention also provides a preparation method of the composition. The preparation method subjects the poria cocos, the coix seeds and the kudzuvine roots to steaming, drying and pulverizing, and mixing the obtainedmixture with other components to obtain the composition suitable for administration.

The invention provides a polypeptide containing a T helper cell epitop (Th epitope), which can serve as an immune stimulus of a B-cell epitope or a peptide hapten for forming a polypeptide immunogen,and application of polypeptide. The B-cell epitope or the peptide hapten is covalently connected with polypeptide through a connecting peptide to form the polypeptide immunogen; the polypeptide-containing polypeptide immunogen is obtained through repeated screening and analyzing of mice, so that the immunogenicity of the B-cell epitope or the peptide hapten can be enhanced remarkably, an antibodywhich can be specifically bonded to a target antigen protein can be produced, the immunoregulation of biased Th2 can be enhanced remarkably, and symptoms can be improved. The polypeptide as well as polypeptide-containing immunogen, derivatives and analogues provided by the invention can also be used for recombinant microorganisms and animals or plants and cells which can be genetically modified, so that the recombinant microorganisms and the animals or the plants and the cells which can be genetically modified serve as a production factory to produce vaccines or prepare oral vaccines or produce specific antibodies and derivatives and modifiers for preventing and treating dominant diseases, including but not limited to diabetes and complications, rheumatoid arthritis and the like, and for developing testing agents.

The invention relates to the field of medicine, in particular to composition and usage thereof. The composition is prepared by drug matching of rhizoma smilacis glabrae, endive, plantain herbs and coix seeds, and the function of lowering lithic acid is achieved. On the basis of the drug matching, rhizoma alismatis are added, and the function of further lowering the lithic acid can be enhanced obviously. Furthermore, on the basis of the drug matching, tuna is added, and the function of further lowering the lithic acid can be enhanced obviously. According to the experimental results, the composition has the function of further lowering the lithic acid obviously.

The invention relates to an afternoon tea bag for health preservation in spring. The afternoon tea bag is prepared from the following components in parts by weight: 2-3 parts of spring white tea particles, 2-3 parts of liquorice particles, 1-2 parts of wolfberry fruit particles and 1-2 parts of hawthorn particles. A preparation method of the afternoon tea bag comprises the following steps: after drying a finished product of white tea, grinding the white tea for later use; adding processed honey into raw liquorice tablets, drying at a constant temperature, and grinding the liquorice tablets for later use; after carrying out vacuum freeze-drying on fresh wolfberry fruit, grinding the wolfberry fruit for later use; after carrying out microwave drying on hawthorn, grinding the hawthorn for later use; and after evenly mixing the ground products, carrying out high-temperature sterilization and subpackaging to obtain the afternoon tea bag. According to the afternoon tea bag, materials are reasonably selected and matched based on the principle of health preservation in four seasons, and the prepared afternoon tea bag for health preservation has the characteristics that particles are uniform, nutritional and nourishing effects are achieved, fresh and natural tastes are realized and the like, can improve the immunity of a human body, and is especially suitable for being drunk by the crowd having sleep disorders, catching a cold easily and often feeling tired as well as patients with high blood pressure, high cholesterol and high blood sugar, and suitable for being used as the afternoon tea for health preservation in spring.

The invention provides traditional Chinese medicine powder for treating gout and hyperuricemia and a preparation method thereof. The traditional Chinese medicine powder is prepared from the followingraw materials in percentage by weight: 60 to 70 percent of sunflower disk spongy bodies, 9 to 12 percent of poria cocos, 6 to 8 percent of radix puerariae and 15 to 20 percent of coix seeds. The method comprises the following steps of crushing the sunflower disk spongy body, poria cocos, radix puerariae and coix seed raw materials; weighing the raw materials with the corresponding weight accordingto the mixture ratio; adding 10 times of quantity of purified water; performing program control and sectioned heating to 80 DEG C; performing heat insulation for 2 hours; then, eliminating medicine slag through filtering; performing high-speed centrifugation on the solution by a centrifugation machine; abandoning insoluble materials to obtain a coarse extraction raw solution; filtering the coarseextraction raw solution obtained in step 4 by a molecular weight ultrafiltration membrane to eliminate molecular substances to obtain a purification solution; concentrating the purification solutionto 1/10 volume by a vacuum pressure reduction pump; performing drying by a vacuum drying machine to obtain powder. The active ingredients of poria cocos, radix puerariae and coix seeds are introduced,so that the antigout and uric acid reducing effects of the sunflower disk spongy body extracts are improved.

The invention relates to the field of food, in particular to fructus gardeniae substitutional tea and a method for organoleptic optimization of a formula of the fructus gardeniae substitutional tea. The substitutional tea with specific proportioning components can effectively inhibit the activity of xanthine oxidase. The invention also provides a method for searching the organoleptic optimization of the formula of the fructus gardeniae substitutional tea. The optimal component ratio is finally obtained by establishing an optimization model and researching the influence of the components of the substitutional tea on the sense organs, and therefore, the sensory value of the substitutional tea is greatly improved while efficacy is ensured. According to the invention, development and utilization of cape jasmine resources are accelerated, a formula optimization thought is provided, economic development is driven, and ecological benefits and social benefits are improved.

The invention relates to the field of nutrient functional foods, in particular to a solid beverage capable of preventing and reducing high blood pressure and high uric acid. The solid beverage is prepared by mixing desalinated whey powder with skimmed milk powder, whole milk powder, konjac powder, chitosan oligosaccharide, a celery seed extract, a corn stigma extract, a radix puerariae extract, afructus perillae extract, a mulberry leaf extract, a ginkgo extract, a haw extract, a lotus leaf extract, a cinnamon extract, a navy bean extract, a coix seed extract, a siraitia grosvenorii extract,a semen cassiae extract, a burdock root extract and compounding nutrients. The solid beverage is rich in nutrients, can reduce blood pressure and uric acid, can also better accelerate metabolism of ahuman body, can promote peristalsis of intestinal tracts, can prevent constipation, can reduce the risk of blood pressure elevation caused by constipation, is collocated according to a traditional Chinese medicine science principle and dietary nutrition rule, does not generate allergy phenomena, and is free from toxic and side effects and safe and reliable.

The invention discloses a pharmaceutical composition for treating hyperuricemia and a preparation method thereof. The pharmaceutical composition is prepared from the following raw material medicines in parts by weight: 2-8 parts of semen coicis, 2-8 parts of Chinese wolfberries, 0.5-3 parts of ampelopsis grossedentata and 0.5-3 parts of licorice roots. The preparation method comprises the following steps: respectively weighing the above desired parts by weight of the semen coicis, the Chinese wolfberries, the ampelopsis grossedentata and the licorice roots for later use; soaking the semen coicis, the Chinese wolfberries and the licorice roots in water, and then successively conducting heating reflux extraction and concentrating to form an extract powder; soaking the ampelopsis grossedentata in water, carrying out heating reflux extraction, and performing concentrating to form another extract powder; and uniformly mixing the obtained extract powders, and adding auxiliary materials to prepare a preparation. Pharmacodynamic tests show that the both medicinal and edible pharmaceutical composition provided by the invention has the effects of invigorating the spleen, tonifying the kidneyand tonifying the liver so as to address root causes and also has the effects of clearing away heat and toxic materials and resolving dampness so as to alleviate symptoms, can remarkably reduce uricacid, and has a relatively good protection effect on function injuries of the liver and the kidney and on pathological changes of the kidney.

The invention discloses a traditional Chinese medicinal compound preparation for treating IgA nephrosis with hyperuricemia, and a preparation method and a use thereof. The traditional Chinese medicinal compound preparation comprises 25-35 parts of buffalo horns, 10-20 parts of dry rehmannia root, 8-16 parts of radix paeoniae rubra, 6-14 parts of Cortex Moutan, 25-35 parts of Lithospermum erythrorhizon, 8-16 parts of Atractylodes lancea, 8-16 parts of Amur Corktree Bark, 8-16 parts of Medicinal Cyathula Root, 25-35 parts of coix seeds, 25-35 parts of Glabrous Greenbrier Rhizome, 8-16 parts of rhizome of Dioscorea septemloba Thunb, 8-16 parts of Semen plantaginis, 8-16 parts of Semen Sinapis albae, 3-9 parts of rheum officinale, 10-20 parts of Rhizoma Atractylodis Macrocephalae and 8-16 parts of hawthorn fruits. The preparation adopting traditional Chinese medicinal components has mild and non-irritating medicinal effects, has the efficacy of clearing heat and cooling blood, and removing dampness and purging turbidity, can reinforce treatment of IgA nephrosis, effectively reduce proteinuria, uric acid and blood fat in order to restore the kidney functions, can treat the IgA nephrosis with hyperuricemia, is safe to take, and also has the advantages of reliable curative effect, and difficult recurrence of hyperuricemia.

The invention provides a composition suitable for people with gout. The composition suitable for people with the gout is prepared from the following raw materials in parts by mass: 15-20 parts of mulberry powder, 10-20 parts of tomato powder, 10-20 parts of lotus leaf powder, 10-15 parts of grape skin powder, 10-15 parts of grape seed powder, 1-5 parts of resveratrol, 1-5 parts of anthocyanin, 1-5parts of vitamin C, 5-10 parts of resistant dextrin, 0.5-1 part of tricalcium phosphate and a total of 100 parts. The composition with the addition of the mulberry powder, the tomato powder, the grape skin powder and the grape seed powder is suitable for gouty patients, helps to reduce uric acid and relieve gout symptoms.

The invention belongs to the technical field of feed for tortoises, and discloses a feed for desert type tortoises. The feed comprises, by weight, 55-65% of ryegrass, 8-12% of bagasse, 5-10% of paper mulberry leaves, 5-7% of rice bran, 4-6% of bean pulp, 1-2 % of oat, 0.5-1% of corns, 1-1.5% of soybean hulls, 3-6% of mulberry leaves, 3-6% of plantain herbs, 1-2% of longhairy antenoron herbs, 1-2% of corn stigma, 0.5-0.7% of cuttlefish bones and 0.2-0.3% of mineral substance vitamin. The feed contains appropriate protein and a lot of fibers, not only meets requirements for vital movement of the desert type tortoises, but also promotes the desert type tortoises to grow and develop normally, and meanwhile reduces generation of uric acid substantially, the added mulberry leaves, the plantain herbs, the longhairy antenoron herbs, the corn stigma and the like are rich in fiber and various in effective constituent for promoting discharge of the uric acid and therefore can effectively help the tortoises to discharge calculuses in tortoise bodies, and the raw materials are environmentally friendly and free of contamination.

The present invention belong to the field of Chinese medicine technology, and discloses a Chinese medicine extract and capsule preparation for curing chronic nephritis, renal failure and urinaemia, etc. and their preparation method. Said Chinese medicine extract is made up by using 13 Chinese medicinal materials of astragalus root, American ginseng, poria, ovate atractylodex root, rehmannia flower, cordyceps, eucommia bark, lyceum berry and others through a certain preparation method. Then the obtained extract is placed into the capsule so as to obtain the invented Chinese medicine extract capsule preparation.

The invention relates to a sunflower disc composition for reducing uric acid. The sunflower disc composition is mainly prepared from the following raw material components in parts by mass: 20-30 parts of sunflower discs, 12-20 parts of chicory roots, 10-18 parts of cape jasmine fruits, 10-18 parts of dandelions, 8-16 parts of kudzuvine roots, 6-12 parts of coix seeds, 6-12 parts of konjac, 6-12 parts of red dates and 1-5 parts of chitosan oligosaccharide. The sunflower disc composition for reducing uric acid can effectively reduce uric acid, has the effects of relieving swelling and pain, can integrally condition the human body, is prepared from traditional Chinese medicinal material components, has relatively small side effects and is suitable for long-term use.

The invention discloses a micro effervescent tablet with seaweed and baking soda and a preparation method and application of the micro effervescent tablet. The micro effervescent tablet comprises, bypercentage, 25-50% of baking soda, 1-10% of seaweed powder, 5-20% of fruit powder, 10-40% of lactose, 10-40% of mannitol, 1-15% of a plant extract, 0.02-5% of a buffer agent, 0.2-2% of stevioside and0.3-8% of a lubricant. The micro effervescent tablet similar to natural soda water is compounded with seaweed powder with rich mineral substances and specific fruit powder with rich mineral substances, and a mixture with the buffer agent and the plant extract (dandelion, flos sophorae and lophatherum gracile extracts) is added to the micro effervescent tablet, so that the micro effervescent tablethas high mineral substance content and is good in flavor, more economic and high in bioavailability, also has a small side effect and a function of reliving gastric acid and can further achieve the functions of relieving the joint pain, preventing the gout and reducing the uric acid.