This invention belongs to the field of microbial technology, specifically disclosing a
probiotic microcapsule, its preparation method, and its application in the preparation of products for preventing and treating calf
diarrhea. Targeting the
digestive physiology and
pathogenesis of
diarrhea in calves, this invention prepares A-type and B-type microcapsules with different probiotics, targeting different segments of the
digestive tract for release, and then coats them together to obtain
probiotic microcapsules. Through the combination of microalgae, strains, and formulation design, the
probiotic microcapsules prepared by this invention not only exhibit excellent
acid resistance and superior small intestinal
epithelial barrier repair function, but also can deliver probiotics in a gastrointestinal zone with targeted delivery, effectively inhibiting the proliferation of
pathogenic bacteria and thus better preventing and treating calf
diarrhea.