The invention provides a paste prepared from grape, ginseng fruit and honey, which is prepared from the following raw materials: grape, ginseng fruit, red bean, cashew nut, cantaloupe, garland chrysanthemum, nutrient solution, a proper amount of pure water, honey, walnut oil and spirulina powder. The preparation method includes the following steps: (1) preparing a mixed fruit pulp; (2) preparing a cereal grain pulp; (3) preparing a fruit and vegetable juice; and (4) preparing a nutrient solution; and (5) mixing the mixed fruit pulp, the cereal grain pulp, the fruit and vegetable juice and the nutrient solution, adding walnut oil, spirulina powder and honey, and blending into a paste to obtain a finished product. The paste provided by the invention integrates honey, fruits and vegetables, cereal grains and nourishing herbs scientifically, is rich in taste, can fully supplement the nutrients needed by the human body, and has the health-care effects of enhancing human immunity, tonifying middle-Jiao, replenishing qi, removing toxic materials, caring skin, resisting aging, lowering blood pressure and the like.