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Pinellia tuber extract and its preparation process, medicine composition and use

An extract and a technology of Pinellia ternata, applied in the field of Pinellia ternata extract and its preparation, can solve the problem that the pharmacological research of Pinellia ternata extract has not yet been reported and the like.

Inactive Publication Date: 2009-08-26
GUIZHOU NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the extraction of Pinellia generally adopts the conventional water extraction and alcohol precipitation method or alcohol extraction method, but the pharmacological research on Pinellia extract has not been reported yet.

Method used

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  • Pinellia tuber extract and its preparation process, medicine composition and use
  • Pinellia tuber extract and its preparation process, medicine composition and use
  • Pinellia tuber extract and its preparation process, medicine composition and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0093]Embodiment 1 of the present invention: the preparation of pinellia water extract:

[0094] Take 5kg of dried Pinellia tuber, crush it into coarse powder, add 10 times the amount of water to decoct twice, the first time for 2 hours, and the second time for 1.5 hours, filter, combine the filtrates, concentrate to 60°C and measure the relative density to 1.30 , let cool, add ethanol to make the alcohol content 70%, let it stand overnight, take the supernatant and concentrate under reduced pressure to a thick paste with a relative density of 1.25, dry under reduced pressure at 75°C to obtain 230g of Pinellia water extract.

Embodiment 2

[0095] Embodiment 2 of the present invention: the preparation of Pinellia ethanol extract:

[0096] Take 5kg of pinellia tuber dry product, crush it into a coarse powder, add 8 times the amount of 75% ethanol to reflux and extract twice, each time for 2 hours, filter, combine the filtrates, recover ethanol under reduced pressure, and concentrate the remaining liquid to a relative density of 1.25 The thick paste was dried under reduced pressure to obtain 300 g of Pinellia ethanol extract.

Embodiment 3

[0097] Embodiment 3 of the present invention: the preparation of pinellia petroleum ether extract:

[0098] After pulverizing 5 kg of pinellia tuber dry product, heat and reflux extraction with petroleum ether, extract 3 times with 20 L of petroleum ether each time, combine the extracts, evaporate to dryness under reduced pressure, and obtain 270 g of petroleum ether extract.

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Abstract

The present invention discloses one kind of pinellia tuber extract and its preparation process, medicine composition and use. The pinellia tuber extract is prepared with fresh pinellia tuber, and through air dying, crushing to operate pinellia tuber meal, heat reflux or percolating with organic solvent and / or water for 2-4 times to obtain the extracted liquid, concentrating and drying the extract liquid. The pinellia tuber extract has excellent effects of relieving cough, eliminating phlegm, stopping vomiting, diminishing inflammation, etc. and may be used in treating pneumosilicosis, cough, gastric ulcer, arrhythmia, tumor and other diseases.

Description

Technical field: [0001] The invention relates to a Pinellia pinellia extract, a preparation method, a pharmaceutical composition and an application thereof, and belongs to the technical field of medicines. Background technique: [0002] Pinellia is the dry tuber of Pinellia ternata (Thunb.) Breit, a plant of the family Araceae. It is a commonly used medicine in Southwest China and has a long history of medicinal use. According to the folk medicine experience of the Miao nationality, its tubers can be used medicinally, and have the functions of drying dampness and resolving phlegm, reducing adverse flow and relieving vomiting, dispelling swelling and dispelling stagnation. Pinellia can be used alone or as a compound. In the folk of the Miao nationality, pinellia is compatible with Xuanfuhua, ochre, ginseng, ginger, roasted licorice, jujube, etc. It has the functions of reducing phlegm, nourishing qi and stomach, and is used to treat weak stomach qi and internal resistance of...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8888A61P11/00A61P11/10A61P11/14A61P1/08A61P1/04A61P1/00A61P9/06A61P35/00A61P15/04A61K125/00
Inventor 周欣赵超陈华国汤洪波胡晓娜
Owner GUIZHOU NORMAL UNIVERSITY
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