1 results about "Antiarrhythmic effect" patented technology

This application relates to the field of oral instant-dissolving film preparation technology and provides a sotalol hydrochloride film for oral instant-dissolving drug delivery. The components of the sotalol hydrochloride film of this application include: sotalol hydrochloride, film-forming material, filler, and flavoring agent. The sotalol hydrochloride film of this application uses sotalol hydrochloride as the active ingredient, which can exert an antiarrhythmic effect and regulate myocardial cell repolarization; the use of polyvinyl alcohol as the film-forming material provides the film's formability and flexibility; the addition of mannitol as a filler helps increase the film's solids content, adjust the film's thickness and uniformity, and improve the formability of the oral instant-dissolving film; steviol glycosides and / or blueberry flavoring, as flavoring agents, can mask the bitterness of sotalol hydrochloride, while giving the film a light pink appearance and blueberry flavor, further improving the sensory experience. Therefore, the sotalol hydrochloride film of this application has more accurate dosage, is more convenient to swallow, has a more suitable taste, and is applicable to a wider range of scenarios.