Application of niflumic acid in preventing and treating arrhythmia

A technology of niflufenamic acid and niflufenamic acid, which is applied in niflumic acid, a known drug field, and can solve problems such as adverse side effects
CN1386502AInactive Publication Date: 2002-12-25FOURTH MILITARY MEDICAL UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
FOURTH MILITARY MEDICAL UNIVERSITY
Publication Date
2002-12-25
Estimated Expiration
Not applicable · inactive patent

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Abstract

A novel application of niflumic acid (NFA) in treating arrhythmia is disclosed. It can block the chlorine ion channel to treat the arrhythmia caused by low osmotic pressure and aconitine. It can be also used for auxiliary therapy of hypertension.
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Description

[0001] 1. Field

[0002] The invention relates to a medicine and its application, in particular to the application of a known medicine-niflufenamic acid in antiarrhythmia. 2. Background technology

[0003] Coronary heart disease is a disease that seriously endangers human health, and its serious complication—arrhythmia is one of the main causes of sudden death in patients. Therefore, prevention and treatment of arrhythmia is the key to improving people's quality of life.

[0004] The ion channel on the myocardial cell membrane is the structural basis of the electrical activity of the myocardium, and their opening and closing determine the characteristics of the electrical activity of the myocardium. Due to myocardial ischemia, the electrical activity of the heart is disturbed, resulting in arrhythmia. Therefore, the basic action principles of antiarrhythmic drugs are aimed at ion channels, and by directly or indirectly changing the activity levels of some myocardial ion chan...

Claims

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