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Growth inducing stand for animal tissue

A technology of animal tissue and support layer, applied in medical science, prosthesis, dilator, etc., can solve problems such as unreasonable structure or shape, inflammatory response, and inability to degrade in time, so as to achieve good biocompatibility, avoid pain, The effect of good degradability

Inactive Publication Date: 2009-09-09
TRANSEASY MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Some tissue growth-inducing scaffolds are composed of degradable parts and non-degradable parts. However, the materials of the non-degradable parts are not compatible with the human body. take out
[0010] The structure or shape of some tissue growth-inducing scaffolds is unreasonable, for example, the surface is flat, which is not conducive to the attachment and rapid growth of normal cells, and the speed of organ reconstruction is slow, which cannot make normal human cells participate in organ reconstruction according to the predetermined initial shape. Cannot induce directional growth of cells
[0011] The degradation time of bioengineering materials used in some tissue growth-inducing scaffolds is not well controlled. For example, degradation occurs before organ reconstruction is completed, resulting in stenosis or leakage, or after organ reconstruction is completed, it remains in place for a long time. Stay in the human body and cannot be degraded in time, leading to adverse consequences such as inflammatory reactions

Method used

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  • Growth inducing stand for animal tissue
  • Growth inducing stand for animal tissue
  • Growth inducing stand for animal tissue

Examples

Experimental program
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Effect test

Embodiment 1

[0025] Example 1 Artificial esophagus

[0026] figure 1 A preferred embodiment of the present invention is shown, the tissue growth inducing scaffold can be used for reconstruction of animal esophagus (hereinafter referred to as "artificial esophagus").

[0027] Such as figure 1 As shown, the artificial esophagus of the present invention is in the shape of a hollow tube, including a tube body and anastomotic areas 104 at both ends. The pipe body can be roughly divided into three layers: the support layer 102 , the adhesion layer 120 and the sealing layer 140 . Wherein, the sealing layer 140 is located in the innermost layer, and its two ends are fixed on the surgical anastomotic area 104; the adhesive layer 120 is located in the middle, and the supporting layer is located in the outermost layer, and the supporting layer can also be placed inside the adhesive layer 120 or embedded in the adhesive layer. The interior of layer 120.

[0028] Surgical anastomosis area

[0...

Embodiment 2

[0054] Example 2 Artificial trachea

[0055] Figure 2A and Figure 2B A preferred embodiment of the present invention is shown, the tissue growth inducing scaffold can be used for reconstruction of animal trachea (hereinafter referred to as "artificial trachea").

[0056] Embodiment 2 is very similar to Embodiment 1 in structure, for example, they both include an anastomosis area, a support layer, an adhesion layer and a sealing layer, and the functions of the three structures are also similar, and will not be repeated here. The difference between the two will be highlighted below.

[0057] Since the artificial trachea of ​​the present invention can be used for both trachea and bronchi, the artificial trachea of ​​the present invention can be in the shape of a tube without branches, or can be divided into one or more branches on the main body, as shown in Figure 2A Show. The sealing layer 240 is located at the innermost layer of the tube body and is fixed on the adhesive ...

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Abstract

A scaffold for inducing the growth of animal's tissue, especially for regenerating the damaged tubular organ is a hollow tube made of biocompatible material, which is composed of a supporting layer, a porous attaching layer made of degradable material for attaching tissue or cells to it, and a sealing layer made of degradable material.

Description

technical field [0001] The invention relates to a prosthesis that can be transplanted into an animal body, and more specifically, the invention relates to an animal tissue growth-inducing bracket made of bioengineering materials. The animal tissue growth-inducing scaffold of the present invention is particularly suitable for reconstruction of tubular defect organs. Background technique [0002] Clinically, it is sometimes necessary to remove part or all of a patient's organs due to lesions or damage to certain organs. After some organs are partially or completely resected, it is difficult to regenerate, or their functions cannot be performed by the residual part or other organs through compensation, so the normal life of the patient is often greatly affected. For example, in some patients with esophageal cancer, part of the esophagus will be removed, and the stomach will be raised to match the upper part of the remaining esophagus, thus forming a thoracic stomach, which wil...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/04A61M29/00A61L27/50A61L27/00
Inventor 孟凯华新刘建
Owner TRANSEASY MEDICAL TECH
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