Method of preparing 4-amino-3-phenyl butyric hydrochloride
A technology of phenylbutyric acid hydrochloride and amino, which is applied in the preparation of organic compounds, chemical instruments and methods, and preparation of cyanide reactions, etc. It can solve the problems of complicated operation steps, high price of starting materials, and large pollution in the production process. problems, to achieve the effect of simple production process, low price and high product yield
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Example Embodiment
[0013] Add benzoic acid, methanol and nitromethane in a weight ratio of 1:8:0.5, keep the temperature at 18°C and react for 10 hours, cool and crystallize to 5°C, perform solid-liquid separation, and dry to obtain nitrostyrene.
[0014] The dried nitrostyrene and diethyl malonate are put into the methanol solution, and the nitrostyrene, the diethyl malonate and the methanol solution are configured in a weight ratio of 1:1.40:5. Then, the temperature was raised to 45°C and kept for 2 hours. After stirring to produce methyl a-carbomethoxy-β-phenyl-г-nitrobutyrate, 10% and 2.5% of the weight of nitrostyrene were added to Ni And H 2 . Then, maintaining the temperature at 50° C. and the pressure at 4 MPa for hydrogenation reaction for 12 hours to obtain a-carbomethoxy-β-phenyl-g-tetrahydropyrrolidone.
[0015] The a-carbomethoxy-β-phenyl-г-tetrahydropyrrolidone is heated to 80°C, and a-carbomethoxy-β-phenyl-г-tetrahydropyrrolidone twice the hydrochloric acid is added dropwise to hydr...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap