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Method for preparing total aponins of sea cucumber and application in medical fields of said medicine

A technology of plum blossom ginseng and ginsenosides, which is applied to the field of plum blossom ginseng extract and total saponins, can solve the problems of few researches on the preparation method of plum blossom ginseng total saponins, and achieves a technology with significant medicinal effect, large processing capacity and strong controllability. Effect

Inactive Publication Date: 2007-10-03
巫军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The existing literature is mainly about the extraction process and content determination of plum flower ginseng polysaccharides in plum flower ginseng, and there are few studies on the preparation method of plum flower ginseng total saponins

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] 500g dried plum blossom ginseng with viscera removed, extracted three times with 65% ethanol, the dosage is 2000ml each time, let stand for 1 week each time, filter and concentrate the three extracts until alcohol-free, absorb with macroporous resin, wash with water until free color, first eluted with 30% ethanol, then eluted with 60% ethanol, concentrated the 60% ethanol eluate, and dried to obtain 105g, with aglycone content of 18%.

Embodiment 2

[0024] 500g dried whole plum blossom ginseng with viscera removed, standing and extracting with 75% ethanol for three times, the dosage is 2000ml each time, standing for 1 week each time, filtering and combining the filtrate, the filtrate is concentrated and put on the column, washed with water until colorless, and first washed with 30% ethanol Eluted, then eluted with 60% ethanol, concentrated 60% ethanol eluate, dried to obtain 86g, aglycone content was 47%.

Embodiment 3

[0026] 500g dried whole plum blossom ginseng with viscera removed, standing and extracting with 85% ethanol for three times, the dosage is 2000ml each time, standing for 1 week each time, filtering and combining the filtrate, the filtrate is concentrated and put on the column, washed with water until colorless, and first washed with 30% ethanol Eluted, then eluted with 60% ethanol, concentrated 60% ethanol eluate, dried to obtain 61 g, the aglycon content was 62%.

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PUM

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Abstract

A general saponin of Thelenota ananas, its preparing process, and its application in medicine field are disclosed.

Description

technical field [0001] The invention relates to an extract of plum blossom ginseng, specifically, total saponins extracted from the natural medicine plum blossom ginseng (Thelenota ananas Jaeger), including a preparation method and application of the extract, and belongs to the field of medicine. Background technique [0002] Plum ginseng (Thelenota ananas J.), also known as "pineapple ginseng", is an animal of the family Stichopodidae (Holothuriae) of the marine echinodermata (Echinodermata), and its body shape is very large, generally 700mm long and 100mm wide. About 80mm high, it is widely distributed in my country's Xisha Islands and the southern tip of Taiwan. It has the effects of nourishing liver and kidney, nourishing essence and nourishing blood. [0003] Saponin is one of the main secondary metabolites of Prunella ginseng, the main material basis of its chemical defense, and has various biological activities such as antifungal, anticoagulant, immune regulation, cyto...

Claims

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Application Information

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IPC IPC(8): A61K35/56C07J71/00A61P35/00A61K35/616
Inventor 巫军
Owner 巫军
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