Method for quickly on-line detection of traditional Chinese medicine Kuhuang injection effective ingredient using near infra red spectrum

A technology of near-infrared spectroscopy and active ingredients, which is applied in the detection field of traditional Chinese medicine injection ingredients, can solve the problems of complex sample processing and operation, and difficulty in online detection
CN101078685AInactive Publication Date: 2007-11-28常熟雷允上制药有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
常熟雷允上制药有限公司
Publication Date
2007-11-28
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a method for measuring effective component content in kuhuang injection on line by near-infrared spectroscopy quickly. Effective components in kuhuang injection mainly comprise aloe-emodin, rhein, emodin, chrysophanol, physcion, sophocarpine and matrine so on. Near-infrared absorption spectroscopy collecting kuhuang injection make data of effective component content relate with near-infrared spectroscopy by HPLC method. Calibration model is built by partial least-squares regression method. Quick on-line measurement for effective component in injection can be accomplished. Studying result shows that near-infrared spectroscopy analyzing method can measure effective component in kuhuang injection effectively. The method is provided with simple pretreatment for sample, quick measurement and measuring multiple components at the same time. It can be used in on-line analysis and on-line quality control in tcm manufacture process.
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Description

1. Technical field

[0001] The invention relates to a method for detecting components of traditional Chinese medicine injections, in particular to a method for detecting active components of bitter yellow injections by using near-infrared spectroscopy, so as to realize rapid on-line detection of active components of traditional Chinese medicine injections. 2. Background technology

[0002] Kuhuang injection originated from the famous prescription "Yinchenhao Decoction" in "Treatise on Febrile Diseases" written by Zhang Zhongjing, a famous medical sage in ancient my country. It is a national traditional Chinese medicine protection variety. Kuhuang injection clinically treats various types of liver diseases. It has rapid jaundice reduction and significant enzyme reduction. It can improve immunity and improve clinical symptoms at the same time, and has a high degree of safety. The active ingredients of Kuhuang Injection are mainly aloe-emodin, rhein, emodin, chrysophanol, emodin...

Claims

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