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Rhodiola sacra extractive, medicinal composition containing the same, method for preparing the same and the use thereof

A technology of extract and rhodiola, which is applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as complex ingredients, stability, poor controllability, and complex sources of rhodiola species , to achieve obvious efficacy and strong controllability

Inactive Publication Date: 2008-01-02
CHENGDU WAGOTT PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] However, due to the complex sources of Rhodiola species and the complex components contained, the effective substances of the drug are not clear, and it is difficult to effectively control the usage and dosage of the drug for different indications in clinical use, and the stability and controllability are poor. At present, there is no Reports on corresponding index components for different indications

Method used

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  • Rhodiola sacra extractive, medicinal composition containing the same, method for preparing the same and the use thereof
  • Rhodiola sacra extractive, medicinal composition containing the same, method for preparing the same and the use thereof
  • Rhodiola sacra extractive, medicinal composition containing the same, method for preparing the same and the use thereof

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Embodiment 1

[0027] The preparation of embodiment 1 Rhodiola rosea extract of the present invention:

[0028] 200g of Rhodiola rosea rhizome, 2000ml of 70% ethanol for reflux extraction for 1 hour, filter, then 1000ml of 70% ethanol for extraction for 1 hour, filter, filter residue with 1000ml of 70% ethanol for reflux extraction for 1 hour, combine the extracts, concentrate, concentrate The D101 resin on the liquid was firstly eluted with water, then with 50% ethanol, concentrated and dried the ethanol eluent to obtain 13.5g of extract, and the percentage composition of rosavins as detected by HPLC was 3.51%, and the percentage composition of salidroside was 0.93%.

Embodiment 2

[0029] The preparation of embodiment 2 Rhodiola rosea extract of the present invention:

[0030] 200g of Rhodiola rosea rhizome, 2000ml of 70% ethanol for reflux extraction for 1 hour, filter, then 1000ml of 70% ethanol for extraction for 1 hour, filter, filter residue with 1000ml of 70% ethanol for reflux extraction for 1 hour, combine the extracts, concentrate, concentrate The D101 resin on the liquid was eluted with water first, then with 70% ethanol, concentrated and dried the ethanol eluate to obtain 13.6g of extract, and the percentage composition of rosavins as detected by HPLC was 4.18%, and the percentage composition of salidroside was 0.76%.

Embodiment 3

[0031] The preparation of embodiment 3 Rhodiola rosea extract of the present invention:

[0032] 200g of Rhodiola rosea rhizome, 2000ml of 70% ethanol for reflux extraction for 1 hour, filter, then 1000ml of 70% ethanol for extraction for 1 hour, filter, filter residue with 1000ml of 70% ethanol for reflux extraction for 1 hour, combine the extracts, concentrate, concentrate The D101 resin on the solution was firstly eluted with water, then 30% ethanol, and then 70% ethanol, concentrated and dried the 70% ethanol eluate to obtain 10.9g extract, and the percentage content of rosavins was detected by HPLC It is 8.04%, and the percentage content of salidroside is 0.57%.

[0033] Under the condition that the above-mentioned basic process remains unchanged, Rhodiola rosea extracts of the present invention with different specifications can be obtained by reasonable selection of condition parameters.

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Abstract

The invention provides a gadol extract. The extract comprises rosavins, with the weight proportion being 3.0-10.0%, and the rosavins comprises rosavin, rosarin and rosin. The invention also relates to the method for preparing said extract and utilization. The invention is characterized by distinctive effect and strong controllable.

Description

technical field [0001] The invention relates to a Rhodiola rosea extract, which belongs to the field of medicine. Background technique [0002] Rhodiola is sweet in nature and flavor, puckery, cold, and is used for promoting blood circulation to stop bleeding, clearing lung and relieving cough. Treatment of pneumonia cough, hemoptysis and hemoptysis, women's leucorrhea, external use to treat bruises, scalds and burns. In recent years, studies have shown that Rhodiola has the functions of anti-hypoxia, anti-cold, anti-fatigue, anti-microwave radiation and exciting brain and spinal cord. It can improve the work efficiency of physical and mental work, delay the aging of the body, prevent and treat senile diseases and other functions. The genus Rhodiola (Rhodiola L.) of the Sedum family is a perennial herb or subshrub. There are more than 90 species of Rhodiola in the world, and there are about 80 species in my country. [0003] At present, there are many reports about Rhodio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7034A61K36/41A61K125/00A61P3/10C07H15/18
Inventor 房杰张燕
Owner CHENGDU WAGOTT PHARMA
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