Rhodiola sacra extractive, medicinal composition containing the same, method for preparing the same and the use thereof
A technology of extract and rhodiola, which is applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as complex ingredients, stability, poor controllability, and complex sources of rhodiola species , to achieve obvious efficacy and strong controllability
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Publication Date
- 2008-01-02
- Estimated Expiration
- Not applicable · inactive patent
Smart Images
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Abstract
Description
technical field
[0001] The invention relates to a Rhodiola rosea extract, which belongs to the field of medicine. Background technique
[0002] Rhodiola is sweet in nature and flavor, puckery, cold, and is used for promoting blood circulation to stop bleeding, clearing lung and relieving cough. Treatment of pneumonia cough, hemoptysis and hemoptysis, women's leucorrhea, external use to treat bruises, scalds and burns. In recent years, studies have shown that Rhodiola has the functions of anti-hypoxia, anti-cold, anti-fatigue, anti-microwave radiation and exciting brain and spinal cord. It can improve the work efficiency of physical and mental work, delay the aging of the body, prevent and treat senile diseases and other functions. The genus Rhodiola (Rhodiola L.) of the Sedum family is a perennial herb or subshrub. There are more than 90 species of Rhodiola in the world, and there are about 80 species in my country.
[0003] At present, there are many reports about Rhodio...
Examples
Embodiment 1
[0027] The preparation of embodiment 1 Rhodiola rosea extract of the present invention:
[0028] 200g of Rhodiola rosea rhizome, 2000ml of 70% ethanol for reflux extraction for 1 hour, filter, then 1000ml of 70% ethanol for extraction for 1 hour, filter, filter residue with 1000ml of 70% ethanol for reflux extraction for 1 hour, combine the extracts, concentrate, concentrate The D101 resin on the liquid was firstly eluted with water, then with 50% ethanol, concentrated and dried the ethanol eluent to obtain 13.5g of extract, and the percentage composition of rosavins as detected by HPLC was 3.51%, and the percentage composition of salidroside was 0.93%.
Embodiment 2
[0029] The preparation of embodiment 2 Rhodiola rosea extract of the present invention:
[0030] 200g of Rhodiola rosea rhizome, 2000ml of 70% ethanol for reflux extraction for 1 hour, filter, then 1000ml of 70% ethanol for extraction for 1 hour, filter, filter residue with 1000ml of 70% ethanol for reflux extraction for 1 hour, combine the extracts, concentrate, concentrate The D101 resin on the liquid was eluted with water first, then with 70% ethanol, concentrated and dried the ethanol eluate to obtain 13.6g of extract, and the percentage composition of rosavins as detected by HPLC was 4.18%, and the percentage composition of salidroside was 0.76%.
Embodiment 3
[0031] The preparation of embodiment 3 Rhodiola rosea extract of the present invention:
[0032] 200g of Rhodiola rosea rhizome, 2000ml of 70% ethanol for reflux extraction for 1 hour, filter, then 1000ml of 70% ethanol for extraction for 1 hour, filter, filter residue with 1000ml of 70% ethanol for reflux extraction for 1 hour, combine the extracts, concentrate, concentrate The D101 resin on the solution was firstly eluted with water, then 30% ethanol, and then 70% ethanol, concentrated and dried the 70% ethanol eluate to obtain 10.9g extract, and the percentage content of rosavins was detected by HPLC It is 8.04%, and the percentage content of salidroside is 0.57%.
[0033] Under the condition that the above-mentioned basic process remains unchanged, Rhodiola rosea extracts of the present invention with different specifications can be obtained by reasonable selection of condition parameters.