Non-irritating compositions containing zinc salts

一种组合物、锌盐的技术，应用在真菌剂或其他潜在刺激性治疗剂的凝胶,两种或更多种水溶性锌盐的抗刺激性,乳膏或润滑液中，能够解决没有评价抗刺激性等问题

Inactive Publication Date: 2008-04-16
THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Kelly did not evaluate or describe the anti-irritant beneficial effects of combining low concentrations of water-soluble organozinc salts

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0065] The preparation process of the soap formulation is as follows. Prepare 5% zinc solution (50% zinc gluconate and 50% zinc lactate), add 2 grams of 5% zinc solution to 69.92 deionized water to prepare phase A solution. Add the following ingredients to phase A solution to prepare phase B solution:

[0066] 0.2% Polyox N60K,

[0067] 2.0% Pluronic F 87 Prill,

[0068] 0.4% U-care,

[0069] 0.15 Germall Plus

[0070] Mix the solution after adding the ingredients. Then, the solution is mixed for about 45 minutes or until all ingredients are properly dissolved.

[0071] Add to the above solution (Phase A + Phase B): Phase C solution shown below:

[0072] 1.0% D-L panthenol

[0073] 3.0% Montaline

[0074] 3.0% Incromine oxide L

[0075] 1.0%PxE

[0076] 2.0% glycerin

[0077] 2.0% B65C

[0078] After adding the ingredients, the solution is uniformly mixed.

[0079] The preparation process of phase D solution is as follows:

[0080] Dissolve in 14.0% SD alcohol 40B:

[0081] 0.18% B...

Embodiment 1

[0357] Example 1: General formula of zinc gel (10×)

[0358] Ingredients

[0359] 10% zinc gel can be included in the product. The composition of the zinc gel can vary depending on the product used.

Embodiment -2

[0360] Example-2: Zinc Gel A-1 (% in product) (used in glove / condom coating solution)

[0361] Ingredients

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PUM

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Abstract

The present invention relates to methods and compositions which employ low concentrations of combinations of zinc salts to prevent the irritation of skin or mucous membranes that may be caused by therapeutic agents, by personal hygiene products, by articles such as gloves or condoms, or by various physical, chemical, mechanical, or biological irritants.

Description

[0001] Cross references to related applications [0002] The present invention is a partial continuation of the U.S. Patent Application Serial 11 / 143,012 filed on June 2, 2005. Application 11 / 143,012 is a continuation of the U.S. Patent Application Serial 11 / 031,258 filed on January 7, 2005. These patent applications The entire contents of is included here by reference. [0003] 1 Introduction [0004] The present invention relates to a composition and method for preventing skin or mucous membrane irritation that may be caused by therapeutic agents, personal hygiene products, sanitary or protective products such as gloves, various physical, chemical, mechanical or biological irritants using a combination of low-concentration zinc salts . 2. Background of the invention [0005] The Centers for Disease Control (CDC) estimates that hospital-acquired infections cost the U.S. health care system US$4.5 billion annually, and 80% of infections are spread through direct contact. Althoug...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/00A61K9/14A61K33/32A61K31/555A61K31/195A61K31/155A61K8/36A61K8/365A61K8/368A61K8/42A61K31/14A61K31/315A61Q17/00A61Q19/00
CPCA61K2800/75A61K31/315A61K8/42A61K45/06A61Q19/00A61L15/18A61K8/27A61K8/365A61K8/368A61K8/36A61L31/088A61K31/195A61K8/361A61K31/155A61K31/14A61K33/30A61Q17/005Y02A50/30A61K2300/00A61K33/32
Inventor S·M·莫达克M·S·欣特L·卡拉斯T·高恩克尔I·热拉尔多
Owner THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK
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