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Method for preparing extract of shoulder pole tegument and antineoplastic use of the same

A kind of pole pole extract technology, applied in the field of extract preparation of pole pole skin, can solve the problems such as no reports of anti-tumor effect

Inactive Publication Date: 2008-08-20
JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on the anti-tumor effect of the water-ethanol extract of the root bark and stem bark of the pole.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Preparation of the root bark extract of the stalk:

[0028] Dry 1 kg of the root bark of the pole pole after washing and drying, and then pulverize to obtain a powder, then soak the powder in water or ethanol aqueous solutions of different concentrations (see Table 3) at room temperature for 12 hours, and heat and reflux for extraction 3 times. After 2 hours, filter, combine the filtrates, and evaporate to dryness under reduced pressure to obtain dry paste (GE) of the root bark extract (GE). The yield is shown in Table 3.

[0029] Table 3 Yield of different concentrations of ethanol aqueous extracts from the root bark of the pole

[0030] Concentration of ethanol aqueous solution (%)

Embodiment 2

[0032] The preparation of the stem bark extract of Panax lanceolata:

[0033] Dry 1 kg of the washed and dried stem bark of the pole pole first, then pulverize to obtain powder, then soak the powder with water or ethanol aqueous solution of different concentrations (see Table 4) at room temperature for 12 hours, then heat and reflux for extraction 3 times, each time After 2 hours, filter, combine the filtrates, and evaporate to dryness under reduced pressure to obtain a dry paste (GE) of the stem bark extract of the rhizome. The yield is shown in Table 4.

[0034] Table 4 The yield of the ethanol aqueous solution extract of different concentrations of pole bark

[0035] Concentration of ethanol aqueous solution (%)

Embodiment 3

[0037] The anti-cervical cancer emulsion is prepared by using the dry extract (GE) of the root bark of the cymbidium stalks as a raw material by a method known in the art.

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PUM

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Abstract

The invention discloses a preparation method of an extract of grewia biloba bark and an anti-tumor use of the extract, comprising the steps as follows: drying the grewia biloba root bark or stem bark after cleaning and air drying, grinding to powder, heating reflux extraction 1-3 times of the powder with 0% to 100% ethanol solution, combining the extract together, concentrating, drying, then obtaining the extract. The invention has an advantage that the distinctive anti-tumor effect of the extract of grewia biloba bark is proven by a plurality of experiments.

Description

technical field [0001] The invention relates to the field of natural medicines, in particular to a method for preparing an extract from pole bark (root bark and stem bark) and its antitumor application. technical background [0002] Grewia biloba G.Don is a plant of the genus Grewia in the family Tiliaceae, and there are about 150 species of this genus in the world, which are shrubs or small trees. According to the Flora of my country, there are 27 species and 1 doubtful species in China, mainly distributed in Yunnan, Guangxi, Guangdong and Jiangxi provinces. In some countries and regions in Africa and Asia, some plants of the genus Pedrocarpus are used as folk herbal medicines, and most of them have antibacterial and anti-inflammatory effects. For example, Grewia occidentalis in South Africa and Grewia erythraea in Pakistan are used as traditional herbal medicines to treat wound bacterial infections (D.S.Grierson, A.J.Afolayan. Antibacterial activity of some indigenous pla...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P35/00A61K125/00A61K135/00
Inventor 刘建群吴继梅寇晓莉洪沁
Owner JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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