Chinese medicinal composition for treating gout and preparation method and application thereof

The technology of a composition and a traditional Chinese medicine is applied to the traditional Chinese medicine composition for treating gout and the fields of preparation and use thereof, which can solve the problems of large toxic and side effects, and achieve the effects of low drug toxic and side effects, reasonable prescription and significant therapeutic effect.

Inactive Publication Date: 2009-01-21
ANHUI BIOLOGICAL PEPTIDE IND RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These drugs have defects in treatment. Although they can achieve the effect of controlling symptoms, they have relatively large toxic and side effects, such as fever, allergic rash, abdominal pain, diarrhea, leukopenia and thrombocytopenia, and even liver and kidney dysfunction. These have become their clinical applications. the bottleneck

Method used

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  • Chinese medicinal composition for treating gout and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0094] Poria cocos 2kg Poria cocos 2kg Alisma 2kg capillary 3kg

[0095] Smilax tuckahoe 3kg Astragalus 3kg Achyranthes bidentata 1.5kg Powdered vetch 1.5kg

[0096] Danshen 3kg, Baishao 3kg, Imperata 3kg, Digupi 2kg

[0097] Baiwei 1.5kg Jiaohawthorn 2kg Paojiang 1.5kg Atractylodes macrocephala 1.5kg

[0098] Take the above-mentioned raw materials, add water to decoct 3 times, each time add 10 times the amount of water to decoct for 1.5 hours, filter, collect the extract, concentrate to a concentrated solution with a relative density of 1.10 to 1.15 at 60 ° C, spray dry (into the air) The temperature is 180°C, the air outlet temperature is 100°C), the dry extract powder is added with appropriate amount of lactose, granulated, dried, granulated, and bagged.

[0099] Clinical application:

[0100] Get this granule to treat 40 cases of gout patients. Treatment options: Oral. On the 1st to 3rd day, take 20g each time, 3 times a day, after the 4th day, take 10g each time, onc...

Embodiment 2

[0104] Polyporus 1.5kg, Poria 1kg, Alisma 0.5kg, capillary 1.5kg

[0105] Smilax tuckahoe 2kg Astragalus 2kg Achyranthes bidentata 1kg Powdered vetch 1kg

[0106]Salvia miltiorrhiza 1.5kg White peony 1.5kg Imperata rhizome 2kg Digupi 1.5kg

[0107] Bai Wei 1kg, Jiao Hawthorn 1.5kg, Paojiang 1kg, Atractylodes 1kg

[0108] Take the above-mentioned raw materials, add water to decoct twice, each time add 12 times the amount of water to decoct for 2 hours, filter, collect the extract, concentrate to a concentrated solution with a relative density of 1.00 to 1.10 at 60°C, spray dry (into the air) The temperature is 190°C, the air outlet temperature is 100°C), and the dry extract powder is added with an appropriate amount of starch, granulated, dried, sized, and filled into capsules.

Embodiment 3

[0110] Polyporus 2.5kg, Poria 3kg, Alisma 2.5kg, capillary 3.5kg

[0111] Smilax tuckahoe 4kg Astragalus 4kg Achyranthes bidentata 2kg Powdered vetch 2kg

[0112] Danshen 3.5kg White peony 3.5kg Imperata 4kg Digupi 2.5kg

[0113] Bai Wei 2kg, Jiao Hawthorn 2.5kg, Paojiang 2kg, Atractylodes 2kg

[0114] Take the above-mentioned raw materials, add water to decoct 4 times, each time add 8 times the amount of water to decoct for 1 hour, filter, collect the extract, concentrate to a concentrated solution with a relative density of 1.15 to 1.20 at 60 ° C, spray dry (into the air) The temperature is 190°C, the air outlet temperature is 100°C), the dry extract powder is added with an appropriate amount of microcrystalline cellulose, granulated, dried, sized, and compressed into tablets.

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Abstract

The invention discloses a traditional Chinese medicine composition for curing gout and the preparation method and usage thereof. The composition is characterized in that polyporus, poria, alisma orientale, virgate wormwood, smilax glabra, astragalus, achyranthes, rhizome dioscoreae hypoglaucae, salvia miltiorrhiza, white paeony root, rhizome imperatae, cortex lycii radicis, cynanchum atratum, coke hawthorn, baked ginger, the rhizome of large-headed atractylodes, etc. are mixed according to a certain proportion; then the corresponding preparation is prepared by taking the conventional method of aqueous extract, concentration, drying and then adding preparation excipients. The invention has significant curative effects on gout disease.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating gout, a preparation method and application thereof. It belongs to the field of traditional Chinese medicine. Background technique [0002] Gout is a disease caused by purine metabolism disorder and continuous increase of blood uric acid caused by hereditary or acquired etiology. Clinically, it is characterized by hyperuricemia with recurrent attacks of gouty acute arthritis, tophi deposition, gouty chronic arthritis and joint deformities, substantive lesions such as glomeruli and renal tubules, and uric acid stone formation. The course of the disease is long, and in the later stage, renal failure, arteriosclerosis, coronary heart disease, and cerebrovascular accident are often complicated. Gout is one of the oldest metabolic diseases of human beings, and it is also a worldwide disease all over the world. In my country, with the continuous changes in people's work, lifes...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P19/06
Inventor 王海东周小明
Owner ANHUI BIOLOGICAL PEPTIDE IND RES INST
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