Novel use of Aquilaria sinensis fruit and extract thereof in preparing anti-tumor medicament

An anti-tumor drug, the technology of Agarwood, which is applied in the direction of anti-tumor drugs, drug combinations, and pharmaceutical formulas, can solve the problems of no report on the pharmacological activity of Agarwood fruit, limit the application of Agarwood medicinal materials, and take a long time to prevent cancer. The effect of cell proliferation, control of cancer cell proliferation, and good anti-tumor activity

Active Publication Date: 2009-04-22
INST OF TROPICAL BIOSCI & BIOTECH CHINESE ACADEMY OF TROPICAL AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, whether it is natural or artificial incense, it is difficult and time-consuming, which greatly limits the application of agarwood medicinal materials.
A. chinensis is an evergreen tree, and its fruit resources are very rich, but there are no reports on the pharmacological activities of A. chinensis fruit at home and abroad.

Method used

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  • Novel use of Aquilaria sinensis fruit and extract thereof in preparing anti-tumor medicament
  • Novel use of Aquilaria sinensis fruit and extract thereof in preparing anti-tumor medicament
  • Novel use of Aquilaria sinensis fruit and extract thereof in preparing anti-tumor medicament

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Take 500g of the fruit of Akiras sinensis, air dry and pulverize, soak in 10 times the amount of 95% ethanol for 1 hour, heat and reflux for extraction twice, each time for 1 hour, collect the combined filtrate, recover ethanol, concentrate and dry to obtain 91.8 grams of extract. Grind it into a fine powder, mix well, and pack into capsules.

Embodiment 2

[0036] Take 300g of the fruit of Akiras sinensis, dry and pulverize naturally, soak and extract with 10 times the amount of 75% ethanol for 3 times, each time for 1 hour, collect the combined filtrate, recover ethanol, concentrate and dry to obtain 63.4 grams of extract. Add appropriate amount of auxiliary materials, mix well, and pack into capsules.

Embodiment 3

[0038] Take 400g of the fruit of Akiras sinensis, dry and pulverize naturally, soak in 10 times the amount of 50% ethanol for 1 hour, heat and reflux for extraction twice, each time for 1 hour, collect the combined filtrate, recover ethanol, concentrate and dry to obtain 79.7 grams of extract. Beat it into fine powder, mix well, sieve, and subpackage to make powder.

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Abstract

The invention relates to the field of traditional Chinese medicine and natural medicine, in particular to an Aquilaria sinensis fruit and an extract thereof. The invention also discloses novel application of the Aquilaria sinensis fruit and the extract to preparation of antitumor drugs.

Description

technical field [0001] The invention relates to the fields of traditional Chinese medicines and natural medicines, in particular to the application of the fruit and extracts thereof in the preparation of antitumor drugs. The invention discloses its preparation method and application in medicine. Background technique [0002] Aquilaria sinensis (Lour.) Gilg is a plant of the genus Thymelaeaceae, which is a tropical and subtropical evergreen tree. It is a precious medicinal plant unique to my country and has been listed as a national second-class endangered protection. species. There are about 15 species of Agarwood in the world, distributed in India, Malaysia and southeastern Asia. There are only two species produced in my country, namely Hainan white wood incense [Aquilaria sinensis (Lour.) Gilg] and Yunnan agarwood [Aquilaria yunnanensis S.C.Huang]. Whitewood is a resinous wood called domestic agarwood. Domestic agarwood is widely used. It is a traditional Chinese medicin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/835A61P35/00A61K131/00
Inventor 梅文莉戴好富吴娇林峰
Owner INST OF TROPICAL BIOSCI & BIOTECH CHINESE ACADEMY OF TROPICAL AGRI SCI
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