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Externally used medicament preparation for kicking craving for tobacco and wine

A technology of topical drugs and preparations, applied in the field of topical drug preparations for quitting smoking and alcohol addiction, which can solve problems such as arrhythmia, insomnia, dreaminess, convulsions, coma, and death

Active Publication Date: 2009-05-13
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Cytisine selectively acts on the nicotine receptors in the human brain, and to a certain extent, it exerts a similar effect to nicotine to relieve the withdrawal symptoms that occur during smoking cessation, and blocks the tobacco-induced relapse after smoking cessation. The effect of nicotine on the human body is better for smoking cessation, and it also has a potential effect on resisting alcohol dependence, but it has side effects such as nausea and vomiting, headache, diarrhea, flatulence, dilated pupils, arrhythmia, insomnia and dreaminess. Can cause convulsions, coma, death

Method used

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  • Externally used medicament preparation for kicking craving for tobacco and wine
  • Externally used medicament preparation for kicking craving for tobacco and wine
  • Externally used medicament preparation for kicking craving for tobacco and wine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Example 1. An external pharmaceutical preparation for quitting smoking and alcohol addiction, the active ingredient of which is cytisine.

Embodiment 2

[0065] Example 2. An external pharmaceutical preparation for quitting smoking and alcohol addiction, the active ingredient raw material of which is the pharmaceutically acceptable salt of cytisine.

Embodiment 3

[0066] Example 3. An external pharmaceutical preparation for quitting smoking and alcohol addiction, the active ingredients of which are cytisine and a pharmaceutically acceptable salt of cytisine.

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PUM

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Abstract

The invention relates to an external medicine preparation used for abstaining from craving for tobacco and wine. The external medicine preparation is characterized in that the active ingredient for preparing the medicine is cytisine and / or the pharmaceutically acceptable salt thereof. The external medicine preparation comprises the following active ingredients by the weight percentages: 0.001% to 20% of cytisine or the pharmaceutically acceptable salt thereof and auxiliary materials in balancing amount. The external used medicine can be produced into any pharmaceutically acceptable external dosage form, and has strong practicability when being used for abstaining from craving for tobacco and wine.

Description

technical field [0001] The invention relates to an external pharmaceutical preparation, in particular to an external pharmaceutical preparation for quitting smoking and alcohol addiction. Background technique [0002] Smoking and alcoholism are harmful to human health has become the consensus of mankind, but how to help smokers and alcoholics to effectively quit smoking and alcoholism is a difficult problem. Currently, there are 4 kinds of oral drugs that can be used for smoking cessation: nicotine patch or chewing gum , Bupropion (Zyban), Cytisine (cytisine) tablets, "Varenicline" (Varenicline). Among them, nicotine patches or chewing gums cannot get rid of the dependence of smokers on nicotine, the smoking cessation effect is not ideal, and side effects such as skin allergies, sleep disorders, mouth sores, hiccups or heartburn are caused. Bupropion can stimulate the body to release dopamine and norepinephrine, and partially improve the symptoms of discomfort after quittin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/439A61K9/00A61P25/32A61P25/34
Inventor 肖伟丁岗夏月曹亮孙世顷
Owner JIANGSU KANION PHARMA CO LTD
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