Selfheal, mulberry leaf and wild chrysanthemum dripping pills and preparation method thereof

A technology of Xia Sang Ju and dripping pills, which is applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations with inactive ingredients, etc., can solve problems such as no dripping pill preparations yet

Inactive Publication Date: 2009-10-14
张晴龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] After searching the published patent documents, there are 2 patent

Method used

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  • Selfheal, mulberry leaf and wild chrysanthemum dripping pills and preparation method thereof
  • Selfheal, mulberry leaf and wild chrysanthemum dripping pills and preparation method thereof
  • Selfheal, mulberry leaf and wild chrysanthemum dripping pills and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] The prescription of raw materials: Prunella vulgaris 500g, mulberry leaf 175g, wild chrysanthemum 80g;

[0068] Preparation of extract extract:

[0069] (1) Take the above three kinds of medicines, add 10 times the amount of water to decoct 2-3 times, each time for 1-2 hours, combine the decoction, filter, the filtrate is ultrafiltered, and the part with molecular weight below 1000 is collected, and the ultrafiltrate is collected , Concentrated under reduced pressure to an extract with a relative density of 1.35-1.5, and dried under reduced pressure to obtain 37.5g of extract powder;

[0070] Preparation preparation:

[0071] (1) Preparation of medicinal solution: Take polyethylene glycol 6000 at a ratio of 1:2 between the extract powder and 6000 parts by weight of polyethylene glycol, and add 10% water by weight of polyethylene glycol. Melt at 80°C, add the extract extract, stir well to dissolve and mix; set aside;

[0072] (2) Drip system: transfer the prepared liquid med...

Embodiment 2

[0075] The prescription of raw materials: Prunella vulgaris 475g, mulberry leaf 190g, wild chrysanthemum 90g;

[0076] Preparation of extract powder:

[0077] (2) Take the above three kinds of medicines, add 10 times the amount of water to decoct 2-3 times, each time for 1-2 hours, combine the decoction, filter, and the filtrate consists of ASD-2, SA-1, FL-2 A composite resin column composed of equal amounts of different resins is washed with water and then eluted with 70-80% ethanol. The ethanol eluate is collected, the ethanol is recovered under reduced pressure, and concentrated to an extract with a relative density of 1.35-1.5. Press and dry to obtain 36g of extract powder;

[0078] Preparation preparation:

[0079] (1) Preparation of medicinal solution: Take polyethylene glycol 6000 at a ratio of 1:2.5 between the extract powder and 6000 parts by weight of polyethylene glycol, and add 8% water by weight of polyethylene glycol. Melt at 90°C, add the extract powder, stir well u...

Embodiment 3

[0083] The prescription of raw materials: Prunella vulgaris 525g, mulberry leaf 160g, wild chrysanthemum 70g;

[0084] Preparation of extract powder:

[0085] Take the above three kinds of medicine, add 10 times the amount of water to decoct 2-3 times, each 1-2 hours, combine the decoction, filter, the filtrate is filtered through 0.2-0.3μM microporous membrane, the refined filtrate is concentrated under reduced pressure to An extract with a relative density of 1.35 to 1.5, dried under reduced pressure to obtain 34g of extract powder;

[0086] Preparation preparation:

[0087] (1) Preparation of medicinal solution: Take polyethylene glycol 6000 in a ratio of 1:3 by weight of extract powder and 6000 parts by weight of polyethylene glycol, and add 9% water by weight of polyethylene glycol. Melt at 70°C, add the extract powder, stir well until mixed, set aside;

[0088] (2) Drip system: transfer the prepared liquid medicine to the reservoir, seal it and keep it at 80℃, adjust the liq...

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Abstract

The invention provides selfheal, mulberry leaf and wild chrysanthemum dripping pills prepared by three raw materials of selfheal, mulberry leaf, wild chrysanthemum, and the like and a preparation method thereof. The preparation method comprises the following steps: three raw materials are extracted with water, extracting solution is refined into extractive extract powders through different methods, and the extract powders are added into molten polyethylene glycol, fully stirred, evenly mixed and prepared into dripping pills by a pill dripping machine. The invention has the efficacies of getting fever away, improving eyesight, resolving masses, deswelling, dispersing wind heat, clearing lung and moistening dryness, clearing liver and improving eyesight, dispelling wind and clearing away heat, and the like and is used for symptoms of wind-heat cold, conjunctival congestion, headache, hypertension, dizziness, tinnitus, throat abscess, and the like. Compared with the granular formulation with the same prescription, the dripping pills have better pharmacological effect.

Description

Technical field [0001] The invention belongs to the technical field of pharmacy, and specifically relates to a Xia Sangju dripping pill and a preparation method thereof. technical background [0002] Xia Sangju Granules is a combination of Prunella vulgaris, mulberry leaves and chrysanthemum. It has the functions of clearing fire, improving eyesight, dispelling masses, reducing swelling, dispelling wind and heat, clearing lungs and moisturizing dryness, clearing liver and improving eyesight, dispelling wind and heat, etc. Fengreganmao, red eyes, headache, high blood pressure, dizziness, tinnitus, sore throat, sore swelling and poisoning. As a classic traditional Chinese medicine prescription for clearing away heat and detoxification, its effect is more significant. But we found in our research: this Chinese medicine The granules are added with a large amount of auxiliary materials, and the dosage is large, which is not conducive to the storage and carrying of the medicine. Moreov...

Claims

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Application Information

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IPC IPC(8): A61K36/605A61K9/20A61K47/34A61P9/12A61P11/04A61P17/02A61P25/04A61P31/00A61K47/10
Inventor 张晴龙
Owner 张晴龙
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