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Chemical compound medicament for curing alcohol dependence

A compound preparation, alcohol dependence technology, applied in the field of medicine, to achieve the effect of less side effects and significant therapeutic effect

Inactive Publication Date: 2009-10-21
袁才蔚
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In terms of clinical indications, baclofen is used to relieve skeletal muscle spasms caused by related diseases. In terms of clinical indications, baclofen has not been used for the treatment of alcohol dependence.

Method used

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  • Chemical compound medicament for curing alcohol dependence
  • Chemical compound medicament for curing alcohol dependence

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The raw materials used in the preparation are: GABA B Receptor agonist raw material baclofen, M receptor antagonist raw material trihexyphenidyl hydrochloride, auxiliary material is any one of starch or pregelatinized starch, dextrin, the weight ratio of raw materials is: baclofen is 2.4%, 0.6% trihexyphenidyl hydrochloride, and 97% auxiliary materials, which are made into tablets with conventional equipment and processes.

Embodiment 2

[0026] The raw materials used in the preparation are: GABA B Receptor agonist raw material baclofen, M receptor antagonist raw material trihexyphenidyl hydrochloride, excipients are pregelatinized starch, the weight ratio of raw materials is: baclofen is 1%, trihexyphenidyl hydrochloride is 0.2% , The auxiliary material is 98.8%, and the capsule is made with conventional equipment and technology.

Embodiment 3

[0028] The raw materials used in the preparation are: GABA B Receptor agonist raw material baclofen, M receptor antagonist raw material trihexyphenidyl hydrochloride, auxiliary material is dextrin, the weight ratio of raw materials is: baclofen is 0.3%, trihexyphenidyl hydrochloride is 0.05%, auxiliary material It is 99.65%, and it is made into granules with conventional equipment and techniques.

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Abstract

The invention relates to a chemical compound medicament for curing alcohol dependence. The chemical compound medicament is characterized by containing GABAB receptor stimulating agent baclofen bulk medicament, M receptor antagonist paralest bulk medicament and auxiliary material. The material comprises the following effective components by the weight percent: 0.3-15 of baclofen, 0.05-5of paralest and 80-99.65 of auxiliary material. Taballa or medicament in other forms is prepared by regular methods. The chemical compound medicament has remarkable curative effect and little side effect in the aspects of abstinence, rehabilitation and relapse resistance for alcohol reliers.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a compound preparation of chemical medicine for treating alcohol dependence. Background technique [0002] Alcohol, as a legal addictive substance, has been widely consumed by people for a long time, leading to addiction and abuse, causing huge economic and property losses to individuals, families, and countries, and seriously affecting social stability and security. For this reason people have been looking for medicines that can treat alcohol dependence. [0003] Long-term heavy drinking of alcohol can form alcohol dependence. Its clinical manifestations are as follows: 1. The experience of the dependent person to alcohol: after starting to drink, he will soon realize that he is in a happy mood, talks too much after drinking, and feels nervous and fatigue. Under the domination of this kind of experience, the uninterrupted daily drinking, the individual's thirst for alcohol is ...

Claims

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Application Information

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IPC IPC(8): A61K31/4453A61K31/195A61P25/32
Inventor 袁才蔚
Owner 袁才蔚
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