Production method of polylactic acid coronary stents

A technology of polylactic acid and coronary arteries, applied in the field of medical devices, can solve the problems of high cost, subacute thrombus stent stenosis, and complicated stent preparation process, and achieve the effect of simple production and low production cost

Inactive Publication Date: 2017-06-20
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the permanent stent solves the problem of acute vessel closure and long-term thrombosis after percutaneous transluminal coronary angioplasty (PTCA), problems such as subacute thrombosis and in-stent restenosis follow after stent implantation , and patients with implanted stents need to take anti-platelet aggregation drugs for a long time
Moreover, the preparation process of the stent is complicated and the cost is high, so there is room for improvement

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0010] The present invention will be further described below:

[0011] The invention is composed of polylactic acid, polycaprolactone, polyacrylate, astragalus, ginseng, Ophiopogon japonicus, salvia miltiorrhiza, dalbergia, chuanxiong, poria cocos, pinellia chinensis, betel, scallion, tangerine peel and licorice.

[0012] Specifically, the polylactic acid accounts for 20%, the polycaprolactone accounts for 20%, the polyacrylate accounts for 20%, the astragalus accounts for 5%, the ginseng accounts for 5%, and the Ophiopogon japonicus accounts for 5%. 5%, said Danshen accounted for 5%, said Jiangxiang accounted for 5%, said Chuanxiong accounted for 2%, said Poria cocos accounted for 2%, said Pinellia accounted for 2%, said Trichosanthes accounted for 2%, and said Said scallions accounted for 2%, said tangerine peel accounted for 2%, and said licorice accounted for 3%.

[0013] The specific method is as follows: crush astragalus, ginseng, Ophiopogon japonicus, Salvia miltiorrhi...

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Abstract

The invention discloses a production method of polylactic acid coronary stents. The polylactic acid coronary stents is prepared from the following raw materials of polylactic acid, polycaprolactone, polyacrylate, radix astragali, radix ginseng, radix ophiopogonis, radix salviae miltiorrhizae, lignum dalbergiae odoriferae, rhizoma chuanxiong, poria cocos, processed rhizome pinellia, fructus trichosanthis, bulbus allii macrostemi, tangerine peel and radix glycyrrhizae. Compared with the prior art, the polylactic acid coronary stents are compounded by the materials such as medicines and polylactic acid and the like and are prepared into consumable materials of a 3D printing machine; when the stents are produced, suitable coronary stents can be produced by just inputting patterns suitable for patient stents input into a 3D printing device; the polylactic acid coronary stents are simple to produce; the production cost is reduced; meanwhile, the material rich in medicine components is capable of achieving treatment effect; the polylactic acid coronary stents have values of popularization and application.

Description

technical field [0001] The invention relates to a medical device, in particular to a method for preparing a polylactic acid coronary stent. Background technique [0002] Cardiac stent, also known as coronary artery stent, is a medical device commonly used in cardiac interventional surgery, which has the function of dredging arteries. Cardiac stents first appeared in the 1980s, and experienced the development of metal stents, coated stents, and soluble stents. The main materials are stainless steel, nickel-titanium alloy, or cobalt-chromium alloy. In recent years, interventional therapy has become the mainstream treatment for coronary heart disease, and coronary stent implantation is an important part of interventional therapy. At present, permanent stents are mainly used clinically, and the materials of permanent stents are mainly non-degradable 316L stainless steel and Co-Cr alloy. Although the permanent stent solves the problem of acute vessel closure and long-term throm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/06A61L31/04A61L31/00B33Y70/00B33Y10/00
CPCA61L31/005A61L31/048A61L31/06B33Y10/00B33Y70/00C08L67/04C08L33/08
Inventor 宋春莉
Owner JILIN UNIV
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