Medicament for killing sperms in vitro

A spermicide and drug technology, applied in the field of medicine, can solve the problems of lack of anti-inflammatory and antibacterial, excessive dosage, etc.

Inactive Publication Date: 2011-07-27
SHANDONG PROVINCIAL FAMILY PLANNING INST OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

But this Platycodon grandiflora extract contains saponins and other compounds, and when used, it needs to be used in a large amount, which brings more inconvenience when the slow-release capsule is inserted into the IUD and carried
In addition, Platycodon grandiflorum extract lacks anti-inflammatory and antibacterial effects when it is used alone to kill sperm in vitro

Method used

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  • Medicament for killing sperms in vitro
  • Medicament for killing sperms in vitro

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Embodiment Construction

[0031] A medicine for in vitro spermicide of the present invention comprises the following raw materials in weight ratio, 3-7 mg of Campanulaceae saponin D, 3-5 mg of Fangfeng extract, 3-5 mg of cassia twig extract, and 1 mg of psoralen extract -3 mg and 0.9% saline 130-170 ml.

[0032] Medicine of the present invention is made of the raw material of following weight ratio and can have multiple combinations:

[0033] 1. Platycodon saponin D 5 mg, wind wind extract 4 mg, cassia twig extract 4 mg, psoraleae extract 2 mg and 0.9% normal saline 150 ml.

[0034] 2. Platycodon saponin D 3 mg, wind wind extract 3 mg, cassia twig extract 3 mg, psoralen extract 1 mg and 0.9% normal saline 130 ml.

[0035] 3. Platycodon saponin D 7 mg, wind wind extract 5 mg, cassia twig extract 5 mg, psoraleae extract 3 mg and 0.9% normal saline 170 ml.

[0036] According to the preparation method of a kind of in vitro spermicidal drug of the present invention, 3-7 mg of platycodon saponin D is taken...

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Abstract

The invention discloses a medicament for killing sperms in vitro, which comprises the raw materials in percentage by weight: 3-7mg of platycodin D, 3-5mg of divaricate saposhnikovia extract, 3-5mg of cassia twig extract, 1-3mg of malaytea scurfpea extract and 130-170ml of 0.9 percent physiological saline. The platycodin D, the divaricate saposhnikovia extract, the cassia twig extract, and the malaytea scurfpea extract are added into a vessel for uniformly mixing and then 130-170ml of 0.9 percent physiological saline is added into the vessel for uniformly shaking to obtain the medicament. The medicament is prepared from pure traditional Chinese medicine, can rapidly achieve the aim of killing the sperms in vitro and has better antimicrobial effect and sterilizing effect. The medicament can be prepared into emulsion, suppository and other forms for external contraception of vagina, or can be prepared into sustained-release capsules which are placed in an intrauterine device and are carried to enter a human body, so that the contraception effect of the intrauterine device can be enhanced and no toxic and side effect are generated.

Description

technical field [0001] The invention relates to medicine, which is a medicine for killing sperm in vitro. Background technique [0002] At present, the drugs used to kill sperm in vitro are mainly western medicines. The western medicine with better effect is nonoxynol. Long-term use will seriously affect human health. Although measures such as existing contraceptive devices and condoms have better contraceptive effects, they cannot be used for some groups of people. Therefore, those skilled in the art have been studying pure Chinese medicine preparations for a long time, which are used to kill sperm in vitro, so as to achieve contraception and have no damage to the human body. The applicant once selected Platycodon grandiflorum extract as a spermicidal drug among many traditional Chinese medicines, and experiments have proved that it can kill sperm within one minute. But this Platycodon grandiflora extract contains saponins and other compounds, and when used, it needs to ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/54A61P15/18A61K31/704
Inventor 邱毅王磊光
Owner SHANDONG PROVINCIAL FAMILY PLANNING INST OF SCI & TECH
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