Preparation process for Sappan Wood extract perfusate and application thereof in treating bladder cancer

A preparation process and perfusate technology, applied in the directions of drug delivery, pharmaceutical formulation, etc., can solve the problem of not finding the research report of hematoxylin extract on bladder cancer, etc., and achieve the effect of good development prospect, good therapeutic effect and remarkable curative effect.
CN101904892BInactive Publication Date: 2012-06-06山西华尚汇商贸有限公司
1 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
山西华尚汇商贸有限公司
Publication Date
2012-06-06
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to a preparation method for a Sappan Wood extract, in particular to a preparation process for Sappan Wood extract perfusate and application thereof in treating bladder cancer, which solves the problem of the application of the Sappan Wood extract in treating bladder cancer tumors. The preparation process comprises the following steps: taking and smashing Sappan Wood, carrying out water extracting for three times, combining the extracting solutions obtained by three-time water extracting, and carrying out decompression concentrating; standing overnight, and removing sediments; adding petroleum ether, extracting, and retaining aqueous phase; adding ethyl acetate, extracting, and removing the aqueous phase; carrying out decompression volatilizing to remove all the ethylacetate; weighing dry substances, adding purified water to enable the dry substance content to be 2%, heating for dissolving, standing overnight at room temperature, and filtering out sediments; and freeze-drying, and carrying out split charging. The experiment research result shows that the extract has obvious killing effect on bladder neoplasm cells; and compared with mitomycin, epirubicin, Pirarubicin and other anticancer drugs, which are clinically and frequently used, the Sappan Wood extract perfusate has the advantages of high anticancer activity, less toxicity, safety, effectiveness and the like.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a preparation method of sumac extract, in particular to a preparation process of sumac extract perfusate and its application in treating bladder cancer. Background technique

[0002] Sumac (Caesalpinia sappan Linn.), also known as Sufang, Fangfangmu and Sufang. The hematoxylin heartwood can be used as medicine, and it is mostly harvested in autumn. The white sapwood is removed and dried. The dried heartwood is long cylindrical or half-cylindrical, with a length of 10-100 cm and a diameter of 3-13 cm. The surface is yellow-red to brown-red, with knife-cut marks and common longitudinal cracks. Quality is hard. The cross-section is slightly shiny, with obvious annual rings, and some can be seen with dark brown, pine, and bright star pith, with a slight smell and a slightly astringent taste. Nature and flavor are sweet, salty, flat. GUIXIN, liver, spleen channel. It has the effects of promoting blood circulation and removing b...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More