Preparation technology and production method of new integrative formulation of true warrior decoction
An integrated and production method technology of Zhenwu Decoction, which is applied in pill delivery, pharmaceutical formula, suppository delivery, etc., to achieve the effect of wide target distribution
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Embodiment 1
[0041] Prepare the following raw materials by the aforementioned method:
[0042] Extracts, nanoparticles, microcapsules, nanoparticles.
[0043] The composition of the raw materials used to make the active ingredients is——
[0044] 9 parts of Poria cocos, 9 parts of Zhifuzi, 6 parts of Atractylodes macrocephala, 9 parts of white peony, and 9 parts of ginger.
[0045] Its manufacturing process is as follows:
[0046] In the GMP10000 clean room, the extract, nanoparticles, microcapsules, and nanoparticles are mixed according to the ratio of 4:2:2:2, and the latest version of the "Chinese Pharmacopoeia" preparation part of the hard capsule standard is adopted, without adding excipients, antiseptic The preparation is filled with hard capsules by a full-automatic capsule filling machine to make hard capsules. Then carry out internal and external packaging such as counting, bottling, sealing, pasting labels, coding, and packing. Finally, according to the production batch uniform ...
Embodiment 2
[0048] Prepare the following raw materials by the aforementioned method:
[0049] Water decoction concentrate, nanoliposome, nanoemulsion, microemulsion, nanosuspension.
[0050] The composition of the raw materials used to make the active ingredients is——
[0051] 9 parts of Poria cocos, 9 parts of Zhifuzi, 6 parts of Atractylodes macrocephala, 9 parts of white peony, and 9 parts of ginger.
[0052] Its manufacturing process is as follows:
[0053] In the GMP10000 clean room, the decoction concentrate, nanoliposome, nanoemulsion, microemulsion, and nanosuspension are mixed according to the ratio of 5:1:1:2:1, and the latest version of "Chinese Pharmacopoeia" is used. Part of the soft capsule standard, without adding auxiliary materials and preservatives, adopts a fully automatic soft capsule filling machine to sub-pack soft capsules to make soft capsules. Then carry out internal and external packaging such as counting, bottling, sealing, pasting labels, coding, and packing...
Embodiment 3
[0055] Prepare the following raw materials by the aforementioned method:
[0056] Extract, solid lipid nanoparticles, nanoemulsion.
[0057] The composition of the raw materials used to make the active ingredients is——
[0058] 9 parts of Poria cocos, 9 parts of Zhifuzi, 6 parts of Atractylodes macrocephala, 9 parts of white peony, and 9 parts of ginger.
[0059] Its manufacturing process is as follows:
[0060] In the GMP10000 clean room, the extract, solid lipid nanoparticles, and nanoemulsions are mixed in a ratio of 4:3:3, and the latest version of the "Chinese Pharmacopoeia" preparation part of the film standard is adopted, and the film-forming material is polyvinyl alcohol. Made into a film. Cartoning, sealing, sticking labels, printing codes, packing and other internal and external packaging. Finally, according to the production batch uniform instant sterilization, and issue a sterilization report. The area of each film is 2-40 square centimeters, the drug conten...
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