Delivery of two or more medicaments through a single dose selection and single dispense interface

A technology for distributing interfaces and drugs, which is applied in infusion sets, therapeutic nebulizers, hypodermic injection devices, etc., and can solve the problems of inappropriate and changed pre-mixed formulas of multiple effective drugs.

Inactive Publication Date: 2012-05-16
SANOFI AVENTIS DEUT GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This problem means that pre-mixed formulations of multiple active agents may not be suitable, as these premixed formulations may have a fixed ratio of active ingredients that cannot be changed by the health care provider or user
[0006] There is also the problem of requiring multiple drug mixture treatments, as many users cannot handle delivery systems that must use more than one drug, or make the necessary precise calculations of the required dose combinations

Method used

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  • Delivery of two or more medicaments through a single dose selection and single dispense interface
  • Delivery of two or more medicaments through a single dose selection and single dispense interface

Examples

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Embodiment Construction

[0043] According to specific embodiments of the disclosed drug delivery device, a non-user settable or fixed or predetermined dose of a second drug (adjuvant mixture) and a variable dose of a first drug (primary drug mixture) are delivered via a single output or Medication dispensing interface dispense. The dose of the primary drug set by the user automatically determines the fixed dose of the second drug. In a preferred embodiment, the drug dispense interface is a needle cannula (hollow needle). figure 1 One possible embodiment of the invention is shown, in which a multi-use injection device 10 (housing not shown) has two reservoirs arranged side by side, one containing a first medicament 1 and the other containing a second medicament 2 . As an example, the first drug 1 is insulin. The second drug 2 may be GLP1. Preferably, the reservoirs contain multiple doses of each drug. Each reservoir is preferably self-contained and provided as a sealed and sterile cartridge. These...

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Abstract

A injection system for co-delivery of two medicaments (1, 2) having a drug delivery device (10) containing a primary reservoir containing a first medicament (1) and that has a secondary reservoir containing a second medicament (2) where the drug delivery device (10) has only one dose setter (12) for the primary reservoir and that automatically determines the dose of the second medicament (2). Both medicaments (1, 2) are delivered through a single dispense interface.

Description

technical field [0001] According to specific embodiments, the present application relates to medical devices and methods for delivering at least two medicaments from separate reservoirs using a device having only a single dose setter and a single dispense interface. In particular embodiments, a single delivery procedure initiated by the user results in a non-user-settable dose of the second medicament and a user-variable settable dose of the first medicament to be delivered to the patient. The medicament is contained in two or more dose reservoirs, containers or packages, each of which contains separate (single drug compounds) or pre-mixed (co-formulated multi-drug mixtures) medicaments. The present invention is particularly beneficial in that by controlling and defining the treatment regimen the treatment response can be optimized for a specific target group of patients. Background technique [0002] Certain disease states require treatment with one or more different drugs...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M5/19A61M5/315
CPCA61M5/31553A61M5/31561A61M5/31558A61M5/31593A61M5/3158A61M5/19A61M5/31583A61M5/31585A61M11/007A61M15/0035
Inventor D.T.德索斯马雷兹林特尔M.S.博伊德D.M.利克E.A.马沙尔C.S.史密斯E.L.奥蒂兹D.A.普伦普特里
Owner SANOFI AVENTIS DEUT GMBH
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