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Medicinal composition for treating functional metrorrhagia and preparation method thereof

A technique of uterine bleeding and composition, applied in the field of traditional Chinese medicine composition, can solve problems such as pain of patients

Active Publication Date: 2012-06-06
ZHUZHOU QIANJIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Regarding the treatment of anovulatory DUB, Western medicine mainly uses hormone therapy and hemostatic drugs. If the effect is not good, further surgery and curettage or even hysterectomy can be taken, which will cause great pain to the patient.

Method used

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  • Medicinal composition for treating functional metrorrhagia and preparation method thereof
  • Medicinal composition for treating functional metrorrhagia and preparation method thereof
  • Medicinal composition for treating functional metrorrhagia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The preparation method of embodiment 1 soft capsule

[0023] Take 1000g of Radix Paeoniae Alba and 300g of Panax notoginseng, grind them into coarse powder, add 6 times the amount of 80% ethanol to reflux and extract twice, the first time for 2 hours, and the second time for 1 hour, combine the extracts, filter, and recover the ethanol from the filtrate under reduced pressure. The clear paste with a relative density of 1.08 (60°C), centrifuged (3000 rpm, 5 minutes), and concentrated to a thick paste with a relative density of 1.18 (60°C), set aside; take Leonurus 1000g, Agrimony 1000g, Burnet Add 600g of charcoal and 600g of Puhuang charcoal to decoct twice, add 10 times the amount of water each time, decoct for 1 hour, combine the decoction with water, filter, and concentrate the filtrate to a thick paste with a relative density of 1.18 (60°C). Add ethanol to make the ethanol content reach 70%, let it stand for 24 hours, take the supernatant to recover ethanol, and con...

Embodiment 2

[0024] The preparation method of embodiment 2 pills

[0025] Take 900g of Radix Paeoniae Alba and 200g of Panax notoginseng, grind them into coarse powder, add 6 times the amount of 80% ethanol to reflux and extract twice, the first time for 2 hours, and the second time for 1 hour, combine the extracts, filter, and recover the ethanol from the filtrate under reduced pressure. The clear paste with a relative density of 1.05 (60°C), centrifuged (3000 rpm, 5 minutes), and concentrated to a thick paste with a relative density of 1.20 (60°C), set aside; take 1100g of Motherwort, 1100g of Agrimony, Burnet Add 700g of charcoal and 700g of Puhuang charcoal to decoct twice, add 10 times the amount of water each time, decoct for 1 hour, combine the decoction with water, filter, and concentrate the filtrate to a thick paste with a relative density of 1.20 (60°C). Add ethanol to make the ethanol content reach 70%, let it stand for 24 hours, take the supernatant to recover ethanol, and con...

Embodiment 3

[0026] The preparation method of embodiment 3 particles

[0027] Take 1100g of Radix Paeoniae Alba and 400g of Panax notoginseng, grind them into coarse powder, add 6 times the amount of 80% ethanol to reflux and extract twice, the first time for 2 hours, and the second time for 1 hour, combine the extracts, filter, and recover the ethanol from the filtrate under reduced pressure. The clear paste with a relative density of 1.10 (60°C), centrifuged (3000 rpm, 5 minutes), and concentrated to a thick paste with a relative density of 1.15 (60°C), set aside; take 900g of Motherwort, 900g of Agrimony, Burnet Add 500g of charcoal and 500g of Puhuang charcoal to decoct twice, add 10 times the amount of water each time, decoct for 1 hour, combine the decoction with water, filter, and concentrate the filtrate to a thick paste with a relative density of 1.15 (60°C). Add ethanol to make the ethanol content reach 70%, let it stand for 24 hours, take the supernatant to recover ethanol, and ...

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Abstract

The invention provides a medicinal composition for treating functional metrorrhagia. The medicinal composition is prepared from effective components and a pharmaceutically acceptable carrier, wherein the effective components are prepared from the following raw medicines, by weight, 900-1100 parts of white peony root, 900-1100 parts of Herba Leonuri, 200-400 parts of Panax Notoginseng, 900-1100 parts of Agrimonia eupatoria, 500-700 parts of charred Radix Sanguisorbae and 500-700 parts of charred Cattail Pollen. The medicinal composition can be anyone of various pharmaceutically acceptable dosage forms of a tablet, a pill, a soft capsule or a particle. The invention also provides a preparation method of the medicinal composition. The preparation method comprises the following steps: crushing white peony root and Panax Notoginseng into coarse powder, and preparing a thick medicine paste A through an alcohol extraction process; decocting Herba Leonuri, Agrimonia eupatoria, charred Radix Sanguisorbae and charred Cattail Pollen with water to prepare a thick medicine paste B; and mixing the thick paste A and the thick paste B, and adding proper auxiliary materials. The medicinal composition of the invention, which has the efficacies of stasis dissolving, bleeding stopping, menstruation regulating and blood nourishing, can effectively treat the functional metrorrhagia, and has no adverse effects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a pharmaceutical composition capable of treating functional uterine bleeding. Background technique [0002] Metrorrhagia refers to the menstrual cycle, menstrual period, and menstrual flow are seriously disordered, and the menstrual blood is violently or continuously dripping. It is a frequently-occurring and intractable disease in gynecology. According to some statistics, patients with metrorrhagia account for about 1 / 3 of gynecological outpatient clinics. This disease is equivalent to functional uterine bleeding in Western medicine, and is particularly similar to anovulatory DUB. [0003] Dysfunctional uterine bleeding is abnormal uterine bleeding caused by dysfunction of the neuroendocrine system, referred to as "gong blood", which is one of the common diseases in obstetrics and gynecology. According to statistics, 50% of the disease occurred in menopause, 30% o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P15/00
Inventor 王振勇朱大安刘建武
Owner ZHUZHOU QIANJIN PHARMA
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