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Enrofloxacin injection

A technology of enrofloxacin and injection, applied in the field of injection and preparation thereof, can solve the problems of slow elimination of active substances and slow onset of action, and achieve the effects of fast elimination, rapid onset of action and high blood drug concentration

Inactive Publication Date: 2013-03-27
JIANGSU HFQ BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

[0004] However, currently known enrofloxacin injections have a slow onset of action and slow elimination of active substances

Method used

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Embodiment Construction

[0027] In order to make the technical means, creative features, goals and effects achieved by the present invention easy to understand, the present invention will be further elaborated below in conjunction with specifics.

[0028] The enrofloxacin injection of the present invention comprises the following components in percentage by weight: 1%-10% of enrofloxacin, 0.1-5mol of acid or its mixed acid in excess of 0.1-5mol of enrofloxacin and 0.1-5mol of the solution 0.1-30% of the formulation auxiliary, and the balance is water for injection.

[0029] In the present invention, the enrofloxacin is preferably 2.5%-10%.

[0030] In the present invention, the excess of the acid or its mixed acid to enrofloxacin is preferably 0.1-1 mol.

[0031] In the present invention, the acid is in the form of an open chain or a lactone. If the acid is used in its lactone form, its lactone ring is at least partially hydrolyzed prior to formation of the salt or complex with enrofloxacin.

[003...

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Abstract

The invention aims at disclosing enrofloxacin injection. The injection comprises the following components according to weight percentage: 1%-10% of enrofloxacin, acid which is 0.1mol to 5mol more than the enrofloxacin or 0.1mol to 5mol of other mixed acid, preparation auxiliaries accounting for 0.1%-30% of a solution, and the balance of injection water. Compared with the prior art, the enrofloxacin injection functions rapidly as active substances achieve high blood concentration within a short time after being applied, and the active substances are also eliminated rapidly, so that the enrofloxacin injection is particularly suitable for treatment of animals serving as food products, and the purpose of the enrofloxacin injection is achieved.

Description

technical field [0001] The invention relates to an injection and a preparation method thereof, in particular to an enrofloxacin injection suitable for high-efficiency antibacterial in poultry and animals. Background technique [0002] Enrofloxacin, also known as enfroquinolone carboxylic acid, is a chemically synthesized antibacterial agent belonging to fluoroquinolones (Fluoroquinolones). It is a light yellow or light yellow crystalline powder with a bitter taste and is insoluble in water. Soluble in organic solvents such as sodium hydroxide solution, methanol and cyanogen. The absorption of oral administration and intramuscular injection is rapid and relatively complete, and the blood drug level reaches the peak within 0.5-2 hours. In addition to the central nervous system, drug concentrations in almost all tissues are higher than plasma, which is beneficial to the treatment of systemic infection and deep tissue infection. This product is eliminated through renal and non...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K31/496A61K47/22A61K47/18A61K47/12A61K47/02A61P31/04
Inventor 郭春艳
Owner JIANGSU HFQ BIO TECH CO LTD
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