Application of gel material in tooth extraction

A gel material and extraction technique, applied in the field after tooth extraction, can solve the problems such as the lack of other better treatment methods for the extraction wound, the speed of blood clot formation, and the exposure of the wound, so as to prevent infection and complications. , The effect of promoting the formation of new bone and reducing trauma

Active Publication Date: 2013-04-03
韩冰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to differences in individual physique, blood clots form at different speeds. Many patients after tooth extraction will expose the wound after spitting out cotto

Method used

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  • Application of gel material in tooth extraction
  • Application of gel material in tooth extraction
  • Application of gel material in tooth extraction

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-7

[0036] Preparation of the seaweed polysaccharide hydrogel material: dissolve the seaweed polysaccharide with 0.1 mol / L hydrochloric acid, prepare a solution with a certain concentration, and store it in the refrigerator for later use. Weigh a certain amount of sodium β-glycerophosphate and dissolve it in 1 mL of double distilled water to prepare an aqueous solution. Place the spare seaweed polysaccharide solution and sodium β-glycerophosphate aqueous solution in an ice bath for 15 minutes at the same time. Then the aqueous solution of β-glycerophosphate sodium is dripped drop by drop into the continuously stirring colloid solution with a syringe, after mixing, continue to stir for 20min to form seaweed polysaccharide-sodium glycerophosphate hydrogel material, wherein seaweed polysaccharide accounts for 2% of the total gel weight 40wt%, sodium glycerophosphate accounted for 35wt%. The above three methods were tested separately.

Embodiment 2

[0037] Embodiment 2: Prepare polyvinyl methyl ether-glycerol hydrogel according to the method of Example 1, wherein polyvinyl methyl ether accounts for 50wt% of the total weight of the gel, and glycerol accounts for 15wt%;

Embodiment 3

[0038] Embodiment 3: commercially available chitosan-polyvinyl alcohol-sodium bicarbonate composite hydrogel, wherein chitosan-polyvinyl alcohol accounts for 30wt% of gel gross weight, and sodium bicarbonate accounts for 10wt% of gel gross weight ;

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Abstract

The invention discloses application of a gel material in tooth extraction. The application is characterized in that the gel is applied to a tooth socket after a tooth is extracted to promote bone healing and formation of a new bone; the gel material is temperature-sensitive hydrogel or solvent-sensitive gel; the phase transition temperature of the temperature-sensitive hydrogel is in a range of 25 to 36 DEG C, namely when the temperature is lower than the phase transition temperature, the gel material is liquid, and when the temperature is higher than the phase transition temperature, the gel material is solid; and the solvent-sensitive gel means that the gel material is not dissolved in water but easily dissolved in a solvent, and the gel material is liquid when being dissolved in the solvent and solid after the solvent is reduced.

Description

technical field [0001] The invention relates to the treatment of tooth extraction wounds in alveolar surgery and the fields of oral implantology, in particular to the application of gel materials after tooth extraction to promote bone healing of tooth extraction wounds and induce new bone formation. Background technique [0002] Tooth extraction is the most common clinical operation in alveolar surgery. Tooth extraction, as a surgical operation, will inevitably cause varying degrees of damage to soft and hard tissues in the operative area, resulting in reactions such as bleeding, pain, and swelling. Trigger different degrees of systemic reactions, which can cause the intensification or aggravation of other systemic diseases, and are also prone to complications such as alveolar infection and pain. The trauma that occurs after surgery is called a tooth extraction wound. The healing process of tooth extraction wounds takes a long time, and is often not very smooth. In the actu...

Claims

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Application Information

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IPC IPC(8): A61L15/42A61L15/24A61L15/26A61L15/28A61L15/32A61L15/20
Inventor 韩冰杨莉李佳方明张海锋王颖
Owner 韩冰
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