This invention discloses a method for preparing biomimetic
calcium phosphate particles carrying type III recombinant human collagen, relating to the field of new biomedical materials. The particle formulation, by
mass percentage, contains 50%-90% hydroxyapatite and 10%-50% type III recombinant human collagen. The preparation process involves artificially synthesizing hydroxyapatite precipitate, then compounding it with type III recombinant human collagen. The compounded material is then spread, naturally dried, crushed, and sieved to form particles. The resulting particles have a uniform and controllable particle size. When mixed with blood or water, they can quickly form a high-
viscosity, malleable, and stable filling material, directly adapting to the site preservation requirements of alveolar sockets after tooth extraction. The advantages are: the degradation rate of these particles precisely matches the
bone regeneration rate after site preservation
surgery, efficiently guiding
bone tissue regeneration while significantly shortening the
waiting period for implantation after tooth extraction. This solves the clinical promotion difficulties caused by the long
waiting period and complex operation of site preservation
surgery, contributing to the widespread application of this technology in oral clinical practice.