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Folium ginkgo health product for preventing senile dementia and preparation method thereof

A technology for senile dementia and senile dementia, which is applied in the field of ginkgo biloba health care products for the prevention of senile dementia and the field of preparation thereof, can solve the problems of long taking time, damage to the heart, etc., and achieves enhancement of contractile function, easy acceptance, and guarantee of blood oxygen supply. Effect

Inactive Publication Date: 2014-09-17
JIANGSU GANGCHENG CHINESE MEDICINE HEALTH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is an ingredient in ginkgo biloba called ginkgolic acid. If the dose is too large, or if it is taken for a long time, it will damage the heart.

Method used

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  • Folium ginkgo health product for preventing senile dementia and preparation method thereof
  • Folium ginkgo health product for preventing senile dementia and preparation method thereof
  • Folium ginkgo health product for preventing senile dementia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0047] Preparation: Take fresh ginkgo leaves, wash them, dry them in the oven at 70°C for 9 hours (the time depends on the moisture content of the sample, it can be 8-12 hours), take them out and put them in a drying oven to cool, and crush them with a grinder to pass 60 mesh Sieve, and store the powder in a brown jar.

[0048] Extraction: Prepare 60% ethanol solution (take 640mL95% ethanol and 360mL pure water to make 60% ethanol solution). Take 100g of ginkgo leaf powder in 700mL of 60% ethanol, heat to 60°C-70°C in a water bath, extract for 2 hours, stir once every 10 minutes, filter with gauze, add 700mL of 60% ethanol to the residue, and continue at 60°C-70°C Extract for 2 hours, stir once every 10 minutes, filter through gauze, and combine the extracts. Do parallel experiments at the same time.

[0049] Suction filtration: first use gauze to coarsely filter to remove large particles and precipitate, so as to increase the speed of suction filtration. Install suction fi...

specific Embodiment 2

[0054] Pick 1000g of fresh and tender ginkgo leaves, wash them, dry them in the oven at 70°C for 9 hours, take them out and cool them in a drying oven, crush them through a 60-mesh sieve with a pulverizer, and store the powder in a brown wide-mouth bottle to prepare 60 % ethanol solution (take 640mL of 95% ethanol and 360mL of purified water to make a 60% ethanol solution). Take 1000g of ginkgo leaf powder in 7000mL of 60% ethanol, heat it to 60℃~70℃ in a water bath, extract for 2 hours, stir once every 10min, filter with gauze, add 7000mL of 60% ethanol to the residue, and continue at 60℃~70℃ Extract for 2 hours, stir once every 10 minutes, filter through gauze, and combine the extracts. Do parallel experiments at the same time. First use gauze to filter coarsely to remove large particles and precipitate, so as to increase the speed of suction filtration. Install suction filtration equipment, add a small amount of extract solution to the Buchner funnel for suction filtratio...

specific Embodiment 3

[0055]Pick 500g ginkgo leaves, wash and dry them in an oven at 70°C for 9 hours, take them out and cool them in a drying oven, crush them through a 60-mesh sieve with a grinder, and store the powder in a brown jar to prepare 60% ethanol Solution (take 640mL95% ethanol, 360mL purified water to make 60% ethanol solution). Take 500g of ginkgo leaf powder in 3500mL of 60% ethanol, heat to 60°C-70°C in a water bath, extract for 2 hours, stir once every 10 minutes, filter with gauze, add 35,000mL of 60% ethanol to the residue, and continue at 60°C-70°C Extract for 2 hours, stir once every 10 minutes, filter through gauze, and combine the extracts. Do parallel experiments at the same time. First use gauze to filter coarsely to remove large particles and precipitate, so as to increase the speed of suction filtration. Install suction filtration equipment, add a small amount of extract solution to the Buchner funnel for suction filtration, because ginkgo leaves contain colloidal sedim...

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Abstract

The invention provides a folium ginkgo health product for preventing senile dementia, which comprises raw materials by weight portions: 10-30 portions of folium ginkgo, 10-20 portions of polygala tenuifolia, 10-20 portions of prepared rehmannia root, 10-20 portions of Chinese angelica, 10-20 portions of dogwood, 10-20 portions of root of red-rooted salvia, 10-20 portions of poria with hostwood, 10-20 portions of walnut kernel, 10-20 portions of codonopsis pilosula, 10-20 portions of platycladi seed, 10-20 portions of herba epimedii, 10-20 portions of astragalus mongholicus, 10-20 portions of polygonum multiflorum, 10-20 portions of white paeony root, 10-20 portions of fructus ligustri lucidi, 10-20 portions of bunge cherry seed, 10-20 portions of albizia flower and 10-20 portions of tuber fleeceflower stem. The folium ginkgo is extracted, the effective ingredients of the folium ginkgo are retained, the toxicity is reduced, and medicine directly reaches lesions to regulate qi and blood and balance yin and yang. On the one hand, the brain cell shrinkage function is improved, the conditions of Qi-stagnation and blood stasis and venation with the blood stasis are improved, qi and blood keep unblocked, and the blood oxygen supply of brain tissue is secured; and on the other hand, the damaged brain cell tissue is repaired and activated, and the normal brain function is restored.

Description

technical field [0001] The invention relates to a health-care product for intelligence development containing components derived from plants, in particular to a health-care product of ginkgo biloba for preventing senile dementia and a preparation method thereof. Background technique [0002] Alzheimer's disease (AD), also known as senile dementia, is a degenerative disease of the central nervous system with an insidious onset and a chronic progressive course. It is the most common type of senile dementia. The main manifestations are neuropsychiatric symptoms such as progressive memory impairment, cognitive dysfunction, personality changes, and language barriers, which seriously affect social, occupational, and life functions. The etiology and pathogenesis of AD have not yet been elucidated, and the characteristic pathological changes are extracellular senile plaques formed by the deposition of β-amyloid protein, neurofibrillary tangles formed by hyperphosphorylation of tau p...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/804A61P25/28
Inventor 魏丽红李宇周晓华
Owner JIANGSU GANGCHENG CHINESE MEDICINE HEALTH CO LTD
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